APPA

SKU:BHB21900807
Overview
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APPA (CAS 100750-39-8) is an inhibitor. Relevant to Metabolic Enzyme/Protease and Apoptosis research. Molecular formula C14H13NO3, molecular weight 243.26 g/mol.
CAS Number 100750-39-8
Molecular Weight 243.26 g/mol
Storage See Certificate of Analysis
Options selector
Catalog no. Size
HY-131542-10MG 10 mg
HY-131542-25MG 25 mg
HY-131542-50MG 50 mg
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 10 mg, 25 mg, 50 mg
  • Lead time: made to order; typically ships within 2–3 weeks.
  • Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
  • Shipping: Room temperature in continental US; may vary elsewhere.
  • Upon receipt: store as stated on the Certificate of Analysis; contact us if you need the condition before ordering.
Field Specification
CAS no. 100750-39-8
Applications
  • Functional Assay (In Vitro)
Molecular weight 243.26
Molecular formula C14H13NO3
SMILES CC(N1C(C2=CC=CC=C2)=CC(OC(C)=O)=C1)=O
Storage Refer to Certificate of Analysis (CoA) for storage conditions
Shipping Room temperature in continental US; may vary elsewhere.
Catalog no. (Mfr.) HY-131542
Main SKU BHB21900807
Inhibitors

Compound Overview

APPA is an aldose reductase inhibitor. It can effectively prevent apoptosis and the symptoms of Streptozotocin-induced diabetes by inhibiting the polyol pathway in rats, and it has potential application in diabetic nephropathy (DN) research[1]. It has the molecular formula C14H13NO3 and a molecular weight of 243.26 g/mol.

Physical & Chemical Properties

CAS Number 100750-39-8
Molecular Formula C14H13NO3
Molecular Weight 243.26 g/mol
SMILES CC(N1C(C2=CC=CC=C2)=CC(OC(C)=O)=C1)=O
Signaling Pathway Metabolic Enzyme/Protease; Apoptosis
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping Room temperature in continental US; may vary elsewhere.

Literature Cited

Sources cited in this description. Peer-reviewed publications that used this product are listed under References.

[1]. Zhi-Ming Xiu, et al. 1-Acetyl-5-phenyl-1H-pyrrol-3-ylacetate: An aldose reductase inhibitor for the treatment of diabetic nephropathy. Bioorg Med Chem Lett. 2017 Sep 15;27(18):4482-4487.

Safety

For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.

Q.How long does this take to ship?
A.This item is produced on request and typically ships within 2–3 weeks.
Q.Can this be used in humans or for diagnostics?
A.No. This product is supplied For Research Use Only. It is not for diagnostic or therapeutic procedures and not for human or veterinary use.

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Experience the power of Celltrypse™, c-LEcta's innovative enzyme solution for gentle and efficient cell dissociation. Request your free sample and discover a superior alternative for your cell culture workflows.

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