AS3MT Human

SKU:BHZ11000812
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    Overview
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    Acetylserotonin O-Methyltransferase Human Recombinant Arsenic Methyltransferase (AS3MT) catalyzes the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to trivalent arsenical and may have a role in arsenic metabolism. AS3MT methylates arsenite to produce methylarsonate, Me-AsO3H2, which is reduced by methylarsonate reductase to methylarsonite, Me-As(OH)2. Methylarsonite which is also a substrate, is transformed into the much less toxic complex dimethylarsinate (cacodylate), Me2As(O)-OH.
    Enzyme Type Transferase
    Species Human
    Form Liquid
    Expression System E. coli
    Purity 90.0%
    Gene Symbol AS3MT
    Source Escherichia Coli.
    Available Options
    5µg | 20µg | 1mg
    Options selector
    Catalog no. Size
    ENZ-615-5µg 5µg
    ENZ-615-20µg 20µg
    ENZ-615-1mg 1mg
    Field Specification
    Enzyme Type
    • Transferase
    Expression System
    • E. coli
    Form Liquid
    Formulation AS3MT protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 10% glycerol and 0.15M NaCl.
    Product Type
    • Enzyme
    Purity 90.0%
    Source Escherichia Coli.
    Species Human
    Storage Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
    Target AS3MT

    Product Description

    Acetylserotonin O-Methyltransferase Human Recombinant

    Overview

    Arsenic Methyltransferase (AS3MT) catalyzes the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to trivalent arsenical and may have a role in arsenic metabolism. AS3MT methylates arsenite to produce methylarsonate, Me-AsO3H2, which is reduced by methylarsonate reductase to methylarsonite, Me-As(OH)2. Methylarsonite which is also a substrate, is transformed into the much less toxic complex dimethylarsinate (cacodylate), Me2As(O)-OH.

    Specifications

    Purity Greater than 90.0% as determined by SDS-PAGE.
    Formulation AS3MT protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 10% glycerol and 0.15M NaCl.
    Storage Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
    Expression System Escherichia Coli.

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