ASK1-IN-4

SKU:BHB21901767
Overview
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ASK1-IN-4 (CAS 1427538-26-8) is an inhibitor. Reported to act on ASK1. Relevant to MAPK/ERK Pathway and Apoptosis research. Molecular formula C18H14BrNO4S2, molecular weight 452.34 g/mol.
CAS Number 1427538-26-8
Molecular Weight 452.34 g/mol
Target ASK1
Storage See Certificate of Analysis
Options selector
Catalog no. Size
HY-153761-1MG 1 mg
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 1 mg
  • Lead time: made to order; typically ships within 2–3 weeks.
  • Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
  • Shipping: Room temperature in continental US; may vary elsewhere.
  • Upon receipt: store as stated on the Certificate of Analysis; contact us if you need the condition before ordering.
Field Specification
Target ASK1
CAS no. 1427538-26-8
Applications
  • Functional Assay (In Vitro)
Molecular weight 452.34
Molecular formula C18H14BrNO4S2
SMILES BrC(C=C1)=CC=C1C2=CC=C(O2)/C=C3C(N(C(S/3)=S)CCCC(O)=O)=O
Storage Refer to Certificate of Analysis (CoA) for storage conditions
Shipping Room temperature in continental US; may vary elsewhere.
Catalog no. (Mfr.) HY-153761
Main SKU BHB21901767
Inhibitors

Compound Overview

ASK1-IN-4 is an inhibitor of ASK1 (IC50 = 0.2 μM) that interacts with the ATP-binding site of ASK1[1]. It has the molecular formula C18H14BrNO4S2 and a molecular weight of 452.34 g/mol.

Physical & Chemical Properties

CAS Number 1427538-26-8
Molecular Formula C18H14BrNO4S2
Molecular Weight 452.34 g/mol
SMILES BrC(C=C1)=CC=C1C2=CC=C(O2)/C=C3C(N(C(S/3)=S)CCCC(O)=O)=O
Target ASK1
Signaling Pathway MAPK/ERK Pathway; Apoptosis
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping Room temperature in continental US; may vary elsewhere.

Biological Activity

IC50 & Target

ASK1

0.2 μM (IC50)

Literature Cited

Sources cited in this description. Peer-reviewed publications that used this product are listed under References.

[1]. Starosyla SA,et al. ASK1 pharmacophore model derived from diverse classes of inhibitors. Bioorg Med Chem Lett. 2014 Sep 15;24(18):4418-4423.

Safety

For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.

Q.How long does this take to ship?
A.This item is produced on request and typically ships within 2–3 weeks.
Q.Can this be used in humans or for diagnostics?
A.No. This product is supplied For Research Use Only. It is not for diagnostic or therapeutic procedures and not for human or veterinary use.

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