| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | Fibrillin-1|Asprosin|FBN1|FBN |
| Clonality | |
| Form | Liquid |
| Host | |
| Immunogen | asprosin |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Reactivity | |
| Storage | |
| Target | |
| UniProt # |
Product Overview
Hormone that targets the liver to increase plasma glucose levels. Secreted by white adipose tissue and circulates in the plasma. Acts in response to fasting and promotes blood glucose elevation by binding to the surface of hepatocytes. Promotes hepatocyte glucose release by activating the protein kinase A activity in the liver, resulting in rapid glucose release into the circulation.
Polyclonal Rabbit AntibodyValidated Applications
| Application | Recommended Dilution |
|---|---|
| ELISA | Refer to datasheet |
| Immunohistochemistry | Refer to datasheet |
| Western Blot | Refer to datasheet |
Immunogen & Specificity
Immunogen: asprosin
UniProt/Swiss-Prot: P35555
Product Specifications
| Host Species | Rabbit |
|---|---|
| Clonality | Polyclonal |
| Isotype | IgG |
| Species Reactivity | Human, Mouse |
| Purification Method | Immunogen Affinity Purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Molecular Weight | 20-30 kDa |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
Reactivity Notes
Confirmed reactivity in Human, Mouse samples; validated for ELISA, Immunohistochemistry, Western Blot.
Safety & Handling
- For Research Use Only (RUO). Not intended for diagnostic procedures.
- Shipping: cold-chain shipment (typically with ice packs).
- Upon receipt: store at recommended temperature as soon as possible.
- Sales terms and conditions: Please review prior to ordering.
Related Products
Explore additional antibodies and related detection reagents for Asprosin in the BioHippo catalog.
Asprosin antibody
First, usually it's not suggested to recycle antibodies. After use, buffer system of antibodies has changed. The storage condition of recycled antibodies for different customers also varies. Thus, the performance efficiency of recycled antibodies can’t be guaranteed. Besides, FineTest ever conducted the antibody recycling assay. Assay results show recycling times of different antibodies also varies. Usually, higher antibody titer allows more repeated use. Customers can determine based on experimental requirements.
Notes: After incubation, we recycle rest antibodies to centrifuge tube and store at 4℃. High titer antibodies can be stored for a minimum of one week. Reuse about three times.
Components of FineTest antibody buffer are usually PBS with proclin300 or sodium azide, BSA, 50% glycerol. Common preservative is proclin300 or sodium azide, which is widely applied in the lab and industry.
Most antibodies are stored at -20℃. Directly-labeled flow cytometry antibodies should be stored at 2 - 8℃. The shelf life is one year. If after sales issues for purchased antibodies appear, return or replacement is available. Usually, antibodies can be still used after the one-year warranty. We can offer technical support services.
Directly-labeled flow cytometry antibodies are ready-to-use without dilution. Other antibodies are usually concentrated. Follow the dilution ratio suggested in the manual. Dilute solution for different experiments also varies. Common antibody dilution buffers are acceptable(e.g. PBST, TBST, antibody blocking buffer).
Common retrieval buffers: Tris-EDTA Buffer(pH 9.0); Citrate Buffer(pH 6.0)
Heat induced antibody retrieval:
Method 1: Water-bath heating: Put the beaker with retrieval buffer and slide in the boiling water bath. Keep the boiling state for 15min. Naturally cool to room temperature;
Method 2: Microwave retrieval: Put the beaker with retrieval buffer and slide in the microwave oven. Heat at high power for 5min, Switch OFF for 3min, Heat at medium power for 5min. Naturally cool to room temperature.
BioHippo can support custom antibody formatting and service options for selected products. Contact us to discuss your project requirements.
Potential customization options include:
- Custom conjugation: fluorophore, biotin, enzyme, or nanoparticle labeling available on request for qualified antibodies.
- Bulk or scale-up quantities: volume pricing and custom lead time estimates available for larger orders.
- Alternative formulations: azide-free, carrier protein-free, or lyophilized formats available upon request for selected products.
- OEM and private-label supply: custom packaging and branding available for commercial applications.
Submit your project specifications via the product contact form or reach us at support@ebiohippo.com for a tailored quotation.
Asprosin‐FABP5 Interaction Modulates Mitochondrial Fatty Acid Oxidation through PPARα Contributing to MASLD Development
IF: 14.3 Journal: Advanced Science Author: Department of Pharmacology, SKLFZCD, (State Key Laboratory -Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, Cited Date: 2025-04-25
Asprosin inhibits macrophage lipid accumulation and reduces atherosclerotic burden by up-regulating ABCA1 and ABCG1 expression via the p38/Elk-1 pathway
IF: 8.44 Journal: Journal of Translational Medicine Cited Date: 2022-08-05
Crucial roles of asprosin in cisplatin-induced ferroptosis and acute kidney injury
IF: 7.1 Journal: Free Radical Biology and Medicine Author: Key Laboratory of Targeted Intervention of Cardiovascular Disease, Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, and Department of Physiology, Nanjing Medical University, Nanjing, Jiangsu, 211166, China. Cited Date: 2025-05-02
Anti- Asprosin: A Potential Protective Role Against the Progression of Diabetic Nephropathy in Type 2 Diabetic Rats
IF: 6.25 Journal: American Journal of Biomedical Sciences Cited Date: 2019-09-12
Sex‐specific effects of maternal and post‐weaning high‐fat diet on adipose tissue remodeling and asprosin expression in mice offspring
IF: 5.82 Journal: Molecular Nutrition & Food Research Cited Date: 2021-12-31
Increased RBP4 and Asprosin Are Novel Contributors in Inflammation Process of Periodontitis in Obese Rats
IF: 5.6 Journal: International Journal of Molecular Sciences Author: Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi’an Jiaotong University, Xi’an 710004, China Cited Date: 2023-12-01
Comparison of HIIT and MICT and further detraining on metabolic syndrome and asprosin signaling pathway in metabolic syndrome model of rats
IF: 4.6 Journal: Scientific Reports Author: Department of Exercise Physiology, Faculty of Sport Sciences, University of Guilan, Rasht, Iran. Cited Date: 2024-06-14
The protective effects of humanin in rats with experimental myocardial infarction: The role of asprosin and spexin
IF: 4 Journal: Heliyon Author: Department of Medical Pharmacology, Faculty of Medicine, Adiyaman University, Adiyaman, 02040, Turkey Cited Date: 2023-08-04
Asprosin impairs insulin secretion in response to glucose and viability through TLR4/JNK-mediated inflammation
IF: 3.951 Journal: Molecular and Cellular Endocrinology Cited Date: 2019-03-07
Asprosin, irisin, and meteorin-like protein immunoreactivity in different stages of colorectal adenocarcinoma
IF: 3.309 Journal: Pathology - Research and Practice Cited Date: 2023-04-14
Asprosin contributes to nonalcoholic fatty liver disease through regulating lipid accumulation and inflammatory response via AMPK signaling
IF: 3.2 Journal: Immunity, Inflammation and Disease Author: Department of Infectious Disease, The Affiliated People's Hospital of Ningbo University, Ningbo City, Zhejiang Province, China Cited Date: 2023-08-25
