ATM Inhibitor-9

SKU:BHB21901990
Overview
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ATM Inhibitor-9 (CAS 2951007-81-9) is an inhibitor. Relevant to Cell Cycle/DNA Damage and PI3K/Akt/mTOR research. Molecular formula C25H32N6O2, molecular weight 448.56 g/mol.
CAS Number 2951007-81-9
Molecular Weight 448.56 g/mol
Storage See Certificate of Analysis
Options selector
Catalog no. Size
HY-155091-50MG 50 mg
HY-155091-100MG 100 mg
HY-155091-250MG 250 mg
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 50 mg, 100 mg, 250 mg
  • Lead time: confirmed on inquiry for every option.
  • Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
  • Shipping: Room temperature in continental US; may vary elsewhere.
  • Upon receipt: store as stated on the Certificate of Analysis; contact us if you need the condition before ordering.
Field Specification
CAS no. 2951007-81-9
Applications
  • Functional Assay (In Vitro)
Molecular weight 448.56
Molecular formula C25H32N6O2
SMILES O=C(NC1=NC2=CC(C3=CC=C(N=C3)OCCCN(C)C)=CC=C2N=C1)NC4CCCCC4
Storage Refer to Certificate of Analysis (CoA) for storage conditions
Shipping Room temperature in continental US; may vary elsewhere.
Catalog no. (Mfr.) HY-155091
Main SKU BHB21901990
Inhibitors

Compound Overview

ATM Inhibitor-9 is a potent ATM inhibitor, with an IC50 of 5 nM against ATM kinase, useful for cancer research[1]. It has a molecular formula of C25H32N6O2 and a molecular weight of 448.56 g/mol.

Physical & Chemical Properties

CAS Number 2951007-81-9
Molecular Formula C25H32N6O2
Molecular Weight 448.56 g/mol
SMILES O=C(NC1=NC2=CC(C3=CC=C(N=C3)OCCCN(C)C)=CC=C2N=C1)NC4CCCCC4
Signaling Pathway Cell Cycle/DNA Damage; PI3K/Akt/mTOR
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping Room temperature in continental US; may vary elsewhere.

Literature Cited

Sources cited in this description. Peer-reviewed publications that used this product are listed under References.

[1]. Dexin Deng, et al. Discovery and Evaluation of 3-Quinoxalin Urea Derivatives as Potent, Selective, and Orally Available ATM Inhibitors Combined with Chemotherapy for the Treatment of Cancer via Goal-Oriented Molecule Generation and Virtual Screening. J Med Chem. 2023 Jul 27;66(14):9495-9518.

Safety

For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.

Q.Why is there no price listed?
A.Every size of this product is quoted on inquiry. Send us the size you need and we will come back with price and lead time.
Q.Can this be used in humans or for diagnostics?
A.No. This product is supplied For Research Use Only. It is not for diagnostic or therapeutic procedures and not for human or veterinary use.

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Experience the power of Celltrypse™, c-LEcta's innovative enzyme solution for gentle and efficient cell dissociation. Request your free sample and discover a superior alternative for your cell culture workflows.

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