| Field | Specification |
|---|---|
| Target | |
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C19H25N7O |
| SMILES | |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
ATR-IN-16 is a potent ATR kinase inhibitor that shows anticancer activity in LoVo cells, with an IC50 of 410 nM[1]. It has the molecular formula C19H25N7O (MW 367.45).
Physical & Chemical Properties
| CAS Number | 2756589-62-3 |
|---|---|
| Molecular Formula | C19H25N7O |
| Molecular Weight | 367.45 g/mol |
| SMILES | CC1=NNC(NC2=CC(C3=C(C=NN3C)C)=CC(N4CCOC[C@H]4C)=N2)=C1 |
| Target | ATR |
| Signaling Pathway | Cell Cycle/DNA Damage; PI3K/Akt/mTOR |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
[1]. Bo Shan, et al. Atr inhibitors and uses thereof. WO2022002245A1.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.
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