| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | Sodium aurothiomalate |
| Cas No. | |
| Molecular Weight | |
| Product Type | |
| Signaling Pathway | |
| SMILES | |
| Target |
Compound Overview
Aurothiomalate sodium (CAS 12244-57-4) is a research-grade small molecule supplied by TargetMol.
Alternative names: Sodium aurothiomalate
Physical Properties
| CAS Number | 12244-57-4 |
|---|---|
| Molecular Formula | C4H3AuNa2O4S |
| Molecular Weight | 390.07 g/mol |
| SMILES | OC(CC(S)C(O)=O)=O.(x).(Na).(Au) |
| Form | Solid |
| Shipping | Room Temperature (RT) |
Biological Activity
Sodium aurothiomalate is a gold compound that is used for its immunosuppressive anti-rheumatic effects. Aurothiomalate sodium (Miochrysin) is a potent and selective inhibitor of oncogenic PKC-iota signaling. Aurothiomalate sodium is a potent thioredoxin reductase (TrxR) inhibitor. Aurothiomalate sodium exhibits potent anti-tumor activity.
Target(s): Others, PKC
Signaling pathway(s): Cytoskeletal Signaling, Chromatin/Epigenetic, Others
Safety & Regulatory
For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.
Generally, for molecules that require light-protected storage, we will ship them in amber glass bottles.
The structure of compounds is confirmed through HNMR and purity is verified through HPLC or LCMS, with most compounds having a purity of over 98%. Each batch comes with a Certificate of Analysis (COA), and testing reports are also displayed on our official website.
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).
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