| Field | Specification |
|---|---|
| Target | |
| Alternative names | Vasopressin V1b receptor (V1bR;AVPR V1b;AVPR V3;Antidiuretic hormone receptor 1b;Vasopressin V3 receptor) |
| Gene ID | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human AVPR1B. AA range:271-320 |
| Conjugate | |
| Concentration | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Scientific Background
The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known. [provided by RefSeq, Jul 2008],
Product Overview
This polyclonal antibody, raised in Rabbit, recognizes AVP Receptor V3. It is validated for Immunohistochemistry, Immunofluorescence, ELISA.
Validated Applications
| Applications | Immunohistochemistry, Immunofluorescence, ELISA |
|---|---|
| IHC-p 1 | 50-200, ELISA 1:10000-20000 |
Optimal dilutions should be determined by the end user for each application and sample type.
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human AVPR1B. AA range:271-320
Specifications
| Host | Rabbit |
|---|---|
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human AVPR1B. AA range:271-320 |
| Concentration | 1 mg/mL |
| Subcellular Location | Cell membrane ; Multi-pass membrane protein . |
| Swiss-Prot | P47901 |
| Gene ID | 553 |
| Storage | -20°C/1 year |
Reactivity Notes
Validated reactivity: Human, Mouse, Rat. For other species, epitope conservation may allow cross-reactivity; confirm with appropriate controls.
Safety & Handling
This product is for research use only (RUO) and is not intended for diagnostic or therapeutic use. The formulation contains sodium azide; handle with standard laboratory precautions.
Related Products
Explore related antibodies and reagents for AVP Receptor V3 research from ELK Biotechnology, or contact us for alternative formats.
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