| Field | Specification |
|---|---|
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C12H23N3O2 |
| Purity | |
| SMILES | |
| Form | Solid-Liquid Mixture |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
Azido Myristic Acid is a click chemistry reagent bearing an azide group. It can be used to identify and characterize post-translationally myristoylated proteins through a simple, robust two-step labeling and detection technique[1]. The azide group allows it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAC) with alkyne-containing molecules, as well as ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules bearing DBCO or BCN groups. It is supplied as a white to off-white solid-liquid mixture (C12H23N3O2, MW 241.33) at 99.89% purity.
Physical & Chemical Properties
| CAS Number | 80667-36-3 |
|---|---|
| Molecular Formula | C12H23N3O2 |
| Molecular Weight | 241.33 g/mol |
| Purity | 99.89% |
| Appearance | Solid-Liquid Mixture |
| Color | White to off-white |
| SMILES | [N-]=[N+]=NCCCCCCCCCCCC(O)=O |
| Signaling Pathway | Antibody-Drug Conjugate/ADC Related |
| Solubility | In Vitro: DMSO: 100 mg/mL (414.37 mM; Requires sonication; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO) |
| Storage | Pure form: -20°C, 3 years; 4°C, 2 years. In solvent: -80°C, 6 months; -20°C, 1 month. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description and in the In Vitro & In Vivo Data tab. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with the Safety Data Sheet and your institution's chemical hygiene plan.
In Vitro
| Solvent | Solubility | Notes |
|---|---|---|
| DMSO | 100 mg/mL (414.37 mM) | requires sonication; use freshly opened DMSO (absorbed moisture lowers solubility) |
Aliquot the stock solution and store it at -80°C (up to 6 months) or -20°C (up to 1 month); avoid repeated freeze-thaw cycles.
Data provided by the manufacturer.
In Vitro
Azido Myristic Acid could be a suitable substrate for enzymes. The azide group is very small and is completely absent from natural molecules, so its presence does affect the biodistribution of azido palmitic acid relative to natural palmitic acid, making it a suitable substrate for enzymes.
Data provided by the manufacturer.
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