| Field | Specification |
|---|---|
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C29H40O5S |
| Purity | |
| SMILES | |
| Form | Solid |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
BC-7013 is a novel semi-synthetic pleuromutilin derivative with excellent activity against Gram-positive pathogenic bacteria, including potent antibacterial effects against Staphylococcus, Streptococcus, and penicillin-resistant Streptococcus pneumoniae. It is useful in the research of acute bacterial skin and skin structure infection (ABSSSI)[1]. It is supplied as a white to off-white solid (C29H40O5S, MW 500.69) at 99.04% purity.
Physical & Chemical Properties
| CAS Number | 1028291-66-8 |
|---|---|
| Molecular Formula | C29H40O5S |
| Molecular Weight | 500.69 g/mol |
| Purity | 99.04% |
| Appearance | Solid |
| Color | White to off-white |
| SMILES | O=C(CSC1=CC=CC(CO)=C1)O[C@H]2[C@]3(C)[C@@H](CC[C@]4([C@H]([C@@H]([C@](C=C)(C2)C)O)C)[C@@]3([H])C(CC4)=O)C |
| Signaling Pathway | Anti-infection |
| Solubility | In Vitro: DMSO: 100 mg/mL (199.72 mM; Requires sonication; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO) |
| Storage | 4°C, sealed storage, away from moisture and light. In solvent: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Biological Activity
IC50 & Target
MIC50: 0.015μg/mL (303 tested S. aureus isolates)[2]
Literature Cited
Sources cited in this description and in the In Vitro & In Vivo Data tab. Peer-reviewed publications that used this product are listed under References.
[2]. Biedenbach D J, et al. In vitro antibacterial spectrum of BC-7013, a novel pleuromutilin derivative for topical use in humans. Interscience Conference on Antimicrobial Agents and Chemotherapy. 2009, 49: 199
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with the Safety Data Sheet and your institution's chemical hygiene plan.
In Vitro
| Solvent | Solubility | Notes |
|---|---|---|
| DMSO | 100 mg/mL (199.72 mM) | requires sonication; use freshly opened DMSO (absorbed moisture lowers solubility) |
Aliquot the stock solution and store it at -80°C (up to 6 months) or -20°C (up to 1 month); sealed storage, away from moisture and light; avoid repeated freeze-thaw cycles.
Data provided by the manufacturer.
In Vitro
BC-7013 displays strong inhibition of 303 tested S. aureus isolates, and a MIC50 of 0.015 μg/mL[2]. Against group A streptococci and group B streptococci, BC-7013 is potent, with MIC90 values of 0.03 μg/mL and 0.06 μg/mL, respectively[2].
Data provided by the manufacturer. Numbered citations refer to the Literature Cited list in the product description.
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).
Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close equivalents, or discuss custom synthesis with the right QC documentation (RUO).
