| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | 4-(3-Chloro-2-pyridinyl)-N-[4-(2-methyl-2-propanyl)phenyl]-1-piperazinecarboxamide |
| Cas No. | |
| Form | White Solid |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | Soluble to 100 mM in DMSO and to 40 mM in ethanol |
| Source | Synthetic |
| Storage |
BCTC is an inhibitor of capsaicin- and acid-mediated currents at the TRPV1 receptor, also known as the vanilloid receptor 1. It has demonstrated efficacy in models of acute, inflammatory, and neuropathic pain. In neuroscience, BCTC is used to investigate TRPV1's role in nociception, thermoregulation, and neuroinflammatory processes associated with chronic pain and neurodegeneration.
Classification: Caution: Substance not yet fully tested.
Safety Phrases:
- S22 - Do not breathe dust
- S24/25 - Avoid contact with skin and eyes
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
BCTC (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-307)
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2. Valenzano K.J., et al. (2003) J Pharmacol Exp. Ther. 306(1): 377-386.