| Field | Specification |
|---|---|
| Alternative names | BLM; RECQ2; RECQL3; Bloom syndrome protein; DNA helicase; RecQ-like type 2; RecQ2; RecQ protein-like 3 |
| Gene ID | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Bloom Syndrome. AA range:65-114 |
| Concentration | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Polyclonal Primary AntibodyAnti-BLM rabbit pAb antibody (, -derived) validated for use in multiple research applications. Targets BLM rabbit pAb in validated species samples.
Antibody Specifications
Scientific Background
The Bloom syndrome gene product is related to the RecQ subset of DExH box-containing DNA helicases and has both DNA-stimulated ATPase and ATP-dependent DNA helicase activities. Mutations causing Bloom syndrome delete or alter helicase motifs and may disable the 3'-5' helicase activity. The normal protein may act to suppress inappropriate recombination. [provided by RefSeq, Jul 2008],
Subcellular Location: Nucleus . Together with SPIDR, is redistributed in discrete nuclear DNA damage-induced foci following hydroxyurea (HU) or camptothecin (CPT) treatment. Accumulated at sites of DNA damage in a RMI complex- and SPIDR-dependent manner.
Safety & Handling
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Explore our complete catalog of antibodies, ELISA kits, and life science research reagents at BioHippo.
Store at -20°C for long-term storage. For short-term use (up to 4 weeks), store at 4°C. Avoid repeated freeze-thaw cycles. Centrifuge briefly before opening if condensation is visible.
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
