| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | 2-[(4E,6E)-7-cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxo-1-oxacyclooctadeca-4,6-dien-2-yl]cyclopentane-1-carboxylic acid, 2-[(4E,6E)-7-cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxo-1-oxacyclooctadeca-4,6-dien-2-yl]-1-cyclopentanecarboxylic acid 2-[(4E,6E)-7-cyano-8,16-dihydroxy-18-keto-9,11,13,15-tetramethyl-1-oxacyclooctadeca-4,6-dien-2-yl]cyclopentane-1-carboxylic acid, 7184-60-3, BORRELIDIN, Cyclopentanecarboxylic acid, 2-(7-cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6-dien-2-yl)-, Cyclopentanecarboxylic acid, 2-[(2S,4E,6Z,8R,9S,11R,13S,15S, 16S)-7-cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6-dien-2-yl]-, (1R,2R)-, NSC216128, Cyclopentanecarboxylic acid, 2-(7-cyano-8,16-dihydroxy-9,11, Cyclopentanecarboxylic acid, 2-[(2S,4E,6Z,8R,9S,11R,13S,15S, 16S)-7-cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6-dien-2-yl]-, (1R,2R)-, NSC271295, NSC277295, 2-[(4E,6E)-7-cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxo-1-oxacyclooctadeca-4,6-dien-2-yl]cyclopentane-1-carboxylic acid, Treponemycin |
| Cas No. | |
| Form | White crystalline powder |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | May be dissolved in DMSO or ethanol |
| Source | Fermentation from Streptomyces sp |
| Storage |
Borrelidin is a macrolide antibiotic known for its potent inhibition of threonyl-tRNA synthetase, leading to disruption of protein synthesis. While its primary applications have been in antimicrobial and anticancer research, Borrelidin has also demonstrated anti-angiogenic and anti-inflammatory properties. These characteristics are increasingly relevant to neuroscience, particularly in the study of neurovascular integrity and neuroinflammation. By modulating angiogenesis and inflammatory signaling, Borrelidin may offer insights into the vascular contributions to neurodegenerative diseases. Its unique mechanism of action and broad bioactivity profile make it a valuable compound for exploring novel therapeutic pathways in both oncology and neurology.
WHMIS Classification: Not WHMIS controlled. Not a dangerous substance according to GHS.
Health hazard:
0
Flammability:
0
Physical hazards:
0
Potential Health Effects: Inhalation - May be harmful if inhaled. May cause respiratory tract irritation.
Skin - May be harmful if absorbed through skin. May cause skin irritation.
Eyes - May cause eye irritation.
Ingestion - May be harmful if swallowed.
Borrelidin (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-546)
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