| Field | Specification |
|---|---|
| Alternative names | (trans,trans)-1-Bromo-2,5-bis-(3-hydroxycarbonyl-4-hydroxy)styrylbenzene |
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C24H17BrO6 |
| Purity | |
| SMILES | |
| Form | Solid |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
BSB, also known as (trans,trans)-1-Bromo-2,5-bis-(3-hydroxycarbonyl-4-hydroxy)styrylbenzene, is a Congo red-derived fluorescent probe. It binds not only to extracellular amyloid β protein but also to many intracellular lesions composed of abnormal tau and synuclein proteins, and it acts as a prototype imaging agent for Alzheimer's disease[1]. It is supplied as a light yellow to yellow solid (C24H17BrO6, MW 481.29) at 97.24% purity.
Physical & Chemical Properties
| CAS Number | 291766-06-8 |
|---|---|
| Molecular Formula | C24H17BrO6 |
| Molecular Weight | 481.29 g/mol |
| Purity | 97.24% |
| Appearance | Solid |
| Color | Light yellow to yellow |
| SMILES | BrC1=CC(/C=C/C2=CC=C(O)C(C(O)=O)=C2)=CC=C1/C=C/C3=CC=C(O)C(C(O)=O)=C3 |
| Signaling Pathway | Neuronal Signaling |
| Solubility | In Vitro: DMSO: 100 mg/mL (207.77 mM; Requires sonication and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO) |
| Storage | 4°C, protect from light. In solvent: -80°C, 6 months; -20°C, 1 month (protect from light). |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with the Safety Data Sheet and your institution's chemical hygiene plan.
In Vitro
| Solvent | Solubility | Notes |
|---|---|---|
| DMSO | 100 mg/mL (207.77 mM) | requires sonication and warming and heat to 60°C; use freshly opened DMSO (absorbed moisture lowers solubility) |
Aliquot the stock solution and store it at -80°C (up to 6 months) or -20°C (up to 1 month); protect from light; avoid repeated freeze-thaw cycles.
Data provided by the manufacturer.
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