| Field | Specification |
|---|---|
| Alternative names | Butriptylene |
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C21H27N |
| SMILES | |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
Butriptyline, also known as Butriptylene, is an orally active tricyclic antidepressant that slightly enhances central 5-HT effects. It does not inhibit brain norepinephrine uptake and can be used for depression research[1][2][3]. It has the molecular formula C21H27N (MW 293.45).
Physical & Chemical Properties
| CAS Number | 35941-65-2 |
|---|---|
| Molecular Formula | C21H27N |
| Molecular Weight | 293.45 g/mol |
| SMILES | CC(CN(C)C)CC1C2=CC=CC=C2CCC3=C1C=CC=C3 |
| Signaling Pathway | GPCR/G Protein; Neuronal Signaling |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description and in the In Vitro & In Vivo Data tab. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.
In Vivo
Mice show an anti-obesity effect with Butriptyline (1000 mg/kg; in diet; 10 weeks)[1]. In male albino rats, dose-dependent depression of food reinforced responses is caused by Butriptyline hydrochloride (2.5-30 mg/kg; i.p.; 10-15 day intervals), along with slight depression of the avoidance reflex at the highest doses[2].
| Animal Model | Female CFLP mice, monosodium glutamate (MSG)-induced obesity model[1] |
|---|---|
| Dosage | 1000 mg/kg |
| Administration | In diet, 10 weeks |
| Result | Significantly lowered the body weight. |
Data provided by the manufacturer. Numbered citations refer to the Literature Cited list in the product description.
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