| Field | Specification |
|---|---|
| Alternative names | 2'(3')-O-(4-Benzoylbenzoyl)adenosine-5'-triphosphate tri(triethylammonium) salt |
| CAS no. | |
| Applications | |
| Source | Synthetic |
| Molecular weight | |
| Molecular formula | C24H24N5O15P3•C18H45N3 |
| Purity | |
| Bioactivity | Agonist |
| Activity | |
| Solubility | Soluble in water. |
| SMILES | |
| InChIKey | |
| Form | Off white solid |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
BzATP (2′,3′-O-(4-benzoylbenzoyl)-ATP) is a potent agonist of the P2X7 receptor, exhibiting significantly greater efficacy than ATP. P2X7 receptors are ATP-gated ion channels expressed predominantly in microglia and are key mediators of neuroinflammatory responses. Activation of P2X7 by BzATP induces calcium influx, cytokine release, and inflammasome activation—processes implicated in the pathogenesis of neurodegenerative diseases such as Alzheimer’s, multiple sclerosis, and amyotrophic lateral sclerosis. BzATP is also used to study purinergic signaling and glial cell activation in models of brain injury and chronic inflammation. Its high potency and receptor specificity make it a valuable tool for dissecting neuroimmune mechanisms in the CNS.
Classification: Not WHMIS controlled.
Safety Phrases:
- S22 - Do not breathe dust.
- S24/25 - Avoid contact with skin and eyes.
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
BzATP (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-420)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
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