C8 Ceramide

SKU:BHB11900282
Suppliers
StressMarq Biosciences Inc.
StressMarq Biosciences Inc.
Details Products
Overview
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C8 Ceramide is a research-grade small-molecule activator of Protein kinase for Cell Signaling studies. Supplied as a white waxy solid with 98% purity (CAS 74713-59-0, MW 425.7) soluble in DMSO or 100% ethanol; store at -20°C. For research use only.
Cas No. 74713-59-0
Molecular Formula C26H51NO3
Purity ≥98% (TLC)
Application Notes Protein kinase activator
Options selector
Catalog no. Size
SIH-499-5MG 5 mg
SIH-499-25MG 25 mg
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size (2) — 25 mg, 5 mg.
  • Lead time: options listed as “in stock at manufacturer” typically ship in 2-3 business days; other statuses may take longer.
  • Storage: -20ºC
  • Shipping: ships at ambient temperature.
  • Upon receipt: store at the recommended temperature as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Mfr No SIH-499
Activity
  • Activator
Alternative Names C8-Ceramide
Cas No. 74713-59-0
Form White waxy solid
Molecular Weight 425.7
Product Type
  • Biochemicals
  • Small Molecules
Purity ≥98% (TLC)
Shipping Shipped Ambient
SMILES CCCCCCCCCCCCC/C=C/[C@H]([C@H](CO)NC(=O)CCCCCCC)O
Solubility Soluble in DMSO (25 mg/ml) or 100% ethanol (25 mg/ml)
Source Synthetic
Storage -20ºC

C8 Ceramide is a cell-permeable analog of natural ceramides and functions as a bioactive lipid mediator. It activates protein kinases and induces apoptosis, making it a valuable tool in cell signaling studies. In neuroscience, C8 Ceramide is used to explore mechanisms of programmed cell death and neuroinflammation, both of which are central to neurodegenerative diseases. Its ability to modulate EGF receptor phosphorylation and downstream signaling pathways provides insights into neuronal survival and stress responses.

Classification: Not a hazardous substance or mixture.

Safety Phrases:

  • S22 - Do not breathe dust.
  • S24/25 - Avoid contact with skin and eyes.
  • S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.

C8 Ceramide (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-499)

Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.

  • Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
  • Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
  • Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
  • QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
  • Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).

Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close equivalents, or discuss custom synthesis with the right QC documentation (RUO).

1. Józefowski S., et al. (2010) J. Immun. (Baltimore, Md.: 1950). 185(11): 6960–6973.
2. Gusain A., et al. (2012) Mol.Neurobio. 45(3): 455–464.

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Experience the power of Celltrypse™, c-LEcta's innovative enzyme solution for gentle and efficient cell dissociation. Request your free sample and discover a superior alternative for your cell culture workflows.

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