| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | 2-Phenylethyl (2E)-3-(3,4-dihydroxyphenyl)acrylate, Caffeic acid phenethyl ester |
| Cas No. | |
| Form | Off-White Solid |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | Soluble to 100 mM in DMSO, acetone, ethanol, methanol, acetonitrile |
| Source | Synthetic |
| Storage |
Caffeic Acid Phenethyl Ester (CAPE) is a bioactive compound derived from propolis with potent antioxidant, anti-inflammatory, and neuroprotective properties. It inhibits NF-κB activation, suppresses lipid peroxidation, and modulates signaling pathways involved in cell survival and apoptosis. In neuroscience, CAPE has been studied for its ability to protect neurons from oxidative damage and inflammation, making it a promising candidate for therapeutic development in neurodegenerative diseases such as Parkinson’s and Alzheimer’s.
Classification: Caution: Substance not yet fully tested.
Safety Phrases:
- S22 - Do not breathe dust
- S24/25 - Avoid contact with skin and eyes
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
Hazard Phrases:
H315-H319-H335
Precautionary Phrases:
P261-P305 + P351 + P338
Caffeic Acid Phenethyl Ester (CAPE) (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-263)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).
Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close
equivalents, or discuss custom synthesis with the right QC documentation (RUO).
