Capsaicin

SKU:BHB11900111
Suppliers
StressMarq Biosciences Inc.
StressMarq Biosciences Inc.
Details Products
Overview
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Capsaicin is a research-grade small-molecule biochemical for TRPV1opener supporting Neuroscience and Ion Channels research. Supplied as a off-white solid with >60% purity (CAS 404-86-4, MW 305.41) soluble in DMSO and ethanol; store at -20°C. For research use only.
Cas No. 404-86-4
Molecular Formula C18H27NO3
Purity >60% (HPLC); NMR (conforms)
Application Notes TRPV1opener
Options selector
Catalog no. Size
SIH-322-200MG 200 mg
SIH-322-1G 1 g
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size (2) — 1 g, 200 mg.
  • Lead time: options listed as “in stock at manufacturer” typically ship in 2-3 business days; other statuses may take longer.
  • Storage: -20ºC
  • Shipping: ships at ambient temperature.
  • Upon receipt: store at the recommended temperature as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Mfr No SIH-322
Activity
  • Small Molecules
Alternative Names (6E)-N-(4-Hydroxy-3-methoxybenzyl)-8-methyl-6-nonenamide, 8-Methyl-N-vanillyl-trans-6-nonenamide
Cas No. 404-86-4
Form Off-White Solid
Molecular Weight 305.41
Product Type
  • Biochemicals
  • Small Molecules
Purity >60% (HPLC); NMR (conforms)
Shipping Shipped Ambient
SMILES CC(C)/C=C/CCCCC(=O)NCC1=CC(=C(C=C1)O)OC
Solubility Soluble in DMSO (20 mg/mL) and ethanol (15 mg/mL)
Source Synthetic
Storage -20ºC

Capsaicin is a TRPV1 receptor agonist that activates non-selective cation channels in sensory neurons. It induces the release of substance P and modulates pain signaling pathways. Capsaicin has demonstrated neuroprotective effects in models of cerebral ischemia and is used to study peripheral and central nociceptive mechanisms. Its reversible inhibition of platelet aggregation also suggests vascular implications in neurodegeneration.

Classification: Toxic. May be harmful or fatal if inhaled, swallowed or absorbed through skin.

Safety Phrases:

  • S22 - Do not breathe dust
  • S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
  • S24/25- Avoid contact with shin and eyes

Risk Phrases:

R25-37/38-41-42/43

Hazard Phrases:

H301-H311-H315-H317-H318-H334-H335

Precautionary Phrases:

P261-P280-P301 + P310-P305 + P351 + P338-P342 + P311

Capsaicin (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-322)

Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.

  • Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
  • Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
  • Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
  • QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
  • Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).

Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close equivalents, or discuss custom synthesis with the right QC documentation (RUO).

1. Caterina M.J., et al. (1997) Nature. 389(6653): 816-824.
2. Story G.M., Crus-Orengo L. (2007) Am Scientist. 95(4): 326-333.
3. Vaishnava P., Wang D.H. (2003) Curr Med Chem Cadiovasc Hematol Agents. 1(2): 177-188.

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