| Field | Specification |
|---|---|
| CAS no. | |
| Applications | |
| Source | Microbial — Streptomyces sp. BCC26924 |
| Molecular weight | |
| Molecular formula | C17H19NO3 |
| SMILES | |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
Carbazomycin D shows antituberculosis and antimalarial activity, inhibiting Plasmodium falciparum with an IC50 greater than 10 μg/mL and Mycobacterium tuberculosis with an MIC of 25 μg/mL. It is also cytotoxic to MCF-7, KB, NCI-H187 and Vero cells, with respective IC50 values of 21.3, 33.2, 12.9 and 34.3 μg/mL[1]. It has the molecular formula C17H19NO3 and a molecular weight of 285.34 g/mol.
Physical & Chemical Properties
| CAS Number | 108073-63-8 |
|---|---|
| Molecular Formula | C17H19NO3 |
| Molecular Weight | 285.34 g/mol |
| Structure Classification | Alkaloids Indole Alkaloids |
| SMILES | COC(C(C1=C2)=C3NC1=CC=C2OC)=C(C(C)=C3C)OC |
| Signaling Pathway | Anti-infection |
| Initial Source | Microbial — Streptomyces sp. BCC26924 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
[1]. Intaraudom C, et al. Antimalarial and antituberculosis substances from Streptomyces sp. BCC26924[J]. Tetrahedron, 2011, 67(39): 7593-7597.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.
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