Carnosic acid

Carnosic acid is a phenolic diterpene found in rosemary and sage, known for its potent antioxidant and neuroprotective properties. In neuroscience, carnosic acid has gained attention for its ability to activate the Nrf2-ARE pathway, a critical regulator of cellular defense against oxidative stress. This activation leads to the upregulation of detoxifying and antioxidant enzymes, offering protection against neuronal damage in models of Alzheimer’s, Parkinson’s, and ischemic stroke. Carnosic acid also exhibits anti-inflammatory effects by modulating microglial activation and cytokine production. Its dual action on oxidative stress and inflammation makes it a promising candidate for therapeutic development in neurodegenerative disease research.

Classification: Caution- Substance not yet fully tested.

Safety Phrases:

• S22 - Do not breathe dust
• S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
• S24/25- Avoid contact with skin and eyes

Carnosic acid (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-362)

Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.

• Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
• Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
• Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
• QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
• Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

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