| Field | Specification |
|---|---|
| Target | |
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C16H12N6S |
| Purity | |
| SMILES | |
| Form | Solid |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
Casein kinase 1δ-IN-4 is a potent inhibitor of casein kinase 1δ with potential application in Alzheimer's disease research[1]. It is supplied as a white to off-white solid (C16H12N6S, MW 320.37) at 98.0% purity.
Physical & Chemical Properties
| CAS Number | 851168-98-4 |
|---|---|
| Molecular Formula | C16H12N6S |
| Molecular Weight | 320.37 g/mol |
| Purity | 98.0% |
| Appearance | Solid |
| Color | White to off-white |
| SMILES | CN1N=NN=C1SC2=C3C=CC=CC3=NC(C4=CC=CC=C4)=N2 |
| Target | CK1γ2 |
| Signaling Pathway | Cell Cycle/DNA Damage; Stem Cell/Wnt |
| Solubility | In Vitro: DMSO: 6.67 mg/mL (20.82 mM; Requires sonication and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO) |
| Storage | 4°C, protect from light. In solvent: -80°C, 6 months; -20°C, 1 month (protect from light). |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
[1]. Joseph M. Sheridan, et al. CASEIN KINASE 1δ (CK1δ) INHIBITORS. WO2012080729A2.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with the Safety Data Sheet and your institution's chemical hygiene plan.
In Vitro
| Solvent | Solubility | Notes |
|---|---|---|
| DMSO | 6.67 mg/mL (20.82 mM) | requires sonication and warming and heat to 60°C; use freshly opened DMSO (absorbed moisture lowers solubility) |
Aliquot the stock solution and store it at -80°C (up to 6 months) or -20°C (up to 1 month); protect from light; avoid repeated freeze-thaw cycles.
Data provided by the manufacturer.
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