CCT241161

SKU:BHB11900028
Suppliers
StressMarq Biosciences Inc.
StressMarq Biosciences Inc.
Details Products
Overview
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CCT241161 is a research-grade small-molecule inhibitor of RAF for Cancer and Apoptosis studies. Supplied as a white solid with 98% purity (CAS 1163719-91-2, MW 541.63) soluble in DMSO; store at -20°C. For research use only.
Cas No. 1163719-91-2
Molecular Formula C28H27N7O3S
Purity 98%
Application Notes RAF Inhibitor
Options selector
Catalog no. Size
SIH-186-10MG 10 mg
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 10 mg.
  • Lead time: options listed as “in stock at manufacturer” typically ship in 2-3 business days; other statuses may take longer.
  • Storage: -20ºC
  • Shipping: Blue Ice or 4ºC.
  • Upon receipt: store at the recommended temperature as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Mfr No SIH-186
Activity
  • Inhibitor
Alternative Names 1-(3-(tert-butyl)-1-phenyl-1H-pyrazol-5-yl)-3-(2-(methylthio)-4-((3-oxo-3,4-dihydropyrido[2,3-b]pyrazin-8-yl)oxy)phenyl)urea
Cas No. 1163719-91-2
Form White Solid
Molecular Weight 541.63
Product Type
  • Biochemicals
  • Small Molecules
Purity 98%
Shipping Blue Ice or 4ºC
SMILES CC(C)(C)C1=NN(C2=CC=CC=C2)C(NC(NC(C(SC)=C3)=CC=C3OC4=C5C(NC(C=N5)=O)=NC=C4)=O)=C1
Solubility Soluble in DMSO
Source Synthetic
Storage -20ºC

CCT241161 is a pan-RAF/SFK inhibitor targeting BRAF and SRC kinases with high potency. Though its primary application is in oncology, its relevance to neuroscience stems from SRC kinase inhibition, which affects neuronal signaling and plasticity. SRC family kinases are implicated in neurodegenerative and neuropsychiatric disorders. By modulating these kinases, CCT241161 may contribute to the development of targeted therapies for CNS diseases involving kinase dysregulation and synaptic dysfunction.

Classification: Caution: Substance not yet fully tested.

Safety Phrases:

  • S22 - Do not breathe dust
  • S24/25 - Avoid contact with skin and eyes
  • S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection

CCT241161 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-186)

Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.

  • Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
  • Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
  • Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
  • QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
  • Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).

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1. Girotti, M.R., et al. (2015) Cancer Cell 27.1: 85-96.

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