| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | 1-(3-(tert-butyl)-1-phenyl-1H-pyrazol-5-yl)-3-(2-(methylthio)-4-((3-oxo-3,4-dihydropyrido[2,3-b]pyrazin-8-yl)oxy)phenyl)urea |
| Cas No. | |
| Form | White Solid |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | Soluble in DMSO |
| Source | Synthetic |
| Storage |
CCT241161 is a pan-RAF/SFK inhibitor targeting BRAF and SRC kinases with high potency. Though its primary application is in oncology, its relevance to neuroscience stems from SRC kinase inhibition, which affects neuronal signaling and plasticity. SRC family kinases are implicated in neurodegenerative and neuropsychiatric disorders. By modulating these kinases, CCT241161 may contribute to the development of targeted therapies for CNS diseases involving kinase dysregulation and synaptic dysfunction.
Classification: Caution: Substance not yet fully tested.
Safety Phrases:
- S22 - Do not breathe dust
- S24/25 - Avoid contact with skin and eyes
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
CCT241161 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-186)
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- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
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