| Field | Specification |
|---|---|
| Target | |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | Synthesized peptide derived from the Internal region of human CD206. |
| Conjugate | |
| Purification | |
| Concentration | |
| Storage | |
| Storage buffer | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Scientific Background
The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.
Product Overview
This polyclonal antibody, raised in Rabbit, recognizes CD206. It is validated for Western Blot, Immunohistochemistry.
Validated Applications
| Applications | Western Blot, Immunohistochemistry |
|---|---|
| WB | 1:500-1:2000 |
| IHC | 1:100-1:300 |
Optimal dilutions should be determined by the end user for each application and sample type.
Immunogen
Synthesized peptide derived from the Internal region of human CD206.
Specifications
| Host | Rabbit |
|---|---|
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Species Reactivity | Human |
| Immunogen | Synthesized peptide derived from the Internal region of human CD206. |
| Purification | Affinity Purification |
| Concentration | 1 mg/mL |
| Storage Buffer | PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH 7.4 |
| Calculated MW | 166kDa |
| Observed MW | 170kDa |
| UniProt # | P22897 |
| Lead Time | 2-3 business days |
| Validity | 12 months |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | Ice packs |
| Target Synonyms | bA541I19.1;C type lectin domain family 13 member D;C-type lectin domain family 13 member D;CD 206;CD206;CD206 antigen;CLEC13D;CLEC13DL;Macrophage mannose receptor 1;Macrophage mannose receptor 1 like protein 1;Macrophage mannose receptor;Mannose receptor C type 1;Mannose receptor C type 1 like 1;MMR;MRC 1;MRC1;MRC1;MRC1L1;OTTHUMP00000045206 |
Reactivity Notes
Validated reactivity: Human. For other species, epitope conservation may allow cross-reactivity; confirm with appropriate controls.
Safety & Handling
This product is for research use only (RUO) and is not intended for diagnostic or therapeutic use. The formulation contains sodium azide; handle with standard laboratory precautions.
Related Products
Explore related antibodies and reagents for CD206 research from Elabscience Biotechnology Co Ltd, or contact us for alternative formats.
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