| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | EB-1020 hydrochloride |
| Cas No. | |
| Molecular Weight | |
| Product Type | |
| Signaling Pathway | |
| SMILES | |
| Target |
Compound Overview
Centanafadine hydrochloride (CAS 923981-14-0) is a research-grade small molecule supplied by TargetMol.
Alternative names: EB-1020 hydrochloride
Physical Properties
| CAS Number | 923981-14-0 |
|---|---|
| Molecular Formula | C15H16ClN |
| Molecular Weight | 245.75 g/mol |
| SMILES | (H)(C)12CNC(C)1(C3=CC=C4C=CC=CC4=C3)C2.(H)Cl |
| Form | Solid |
| Shipping | Room Temperature (RT) |
Biological Activity
Centanafadine hydrochloride (EB-1020 hydrochloride) is a dual inhibitor of norepinephrine (NE)/dopamine (DA) transporter, also inhibits serotonin transporter (IC50s: 6 nM, 38 nM, and 83 nM for human NE, DA, and serotonin transporter).
Target(s): Dopamine Receptor, Adrenergic Receptor, Serotonin Transporter, Norepinephrine
Signaling pathway(s): GPCR/G Protein, Neuroscience
Safety & Regulatory
For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.
It is recommended to sonicate at a lower frequency
It is not recommended to store DMSO stock solutions at room temperature. Once the stock solution is prepared, aliquot into single-use volumes and store at −20 °C (or −80 °C for sensitive compounds). Room-temperature storage accelerates chemical degradation and moisture uptake. When ready to use, thaw an aliquot at room temperature, use immediately, and avoid repeated freeze-thaw cycles.
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
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