| Field | Specification |
|---|---|
| Alternative names | Sodium chloro(4-methylbenzenesulfonyl)azanide hydrate |
| CAS no. | |
| Applications | |
| Molecular formula | C7H8ClNO2S·xH2O·Na |
| Purity | |
| SMILES | |
| Form | Solid |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
ChloraMine-T hydrate, also known as Sodium chloro(4-methylbenzenesulfonyl)azanide hydrate, is used as a reagent in various synthetic processes, including aminohydroxylation and allylic amination reactions, as a nitrogen source in aziridination reactions of alkenes, and for deprotection of sulfur groups in sulfur-containing compounds; it has also been used in the synthesis of factor Xa inhibitors. At 0.2% w/v it additionally acts as an antimicrobial agent effective against Staphylococcus epidermidis, Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Proteus mirabilis and Enterococcus cloacae. It is supplied as a white to off-white solid at 98.18% purity.
Physical & Chemical Properties
| CAS Number | 149358-73-6 |
|---|---|
| Molecular Formula | C7H8ClNO2S·xH2O·Na |
| Purity | 98.18% |
| Appearance | Solid |
| Color | White to off-white |
| SMILES | O=S(N([Na])Cl)(C1=CC=C(C)C=C1)=O.[xH2O] |
| Signaling Pathway | Metabolic Enzyme/Protease; Anti-infection |
| Storage | -20°C, sealed storage, away from moisture. In solvent: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
[1]. Agnihotri, et al. Chloramine-T (sodium N-chloro-p-toluenesulfonamide). Synlett 18, 2857-2858 (2005).
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with the Safety Data Sheet and your institution's chemical hygiene plan.
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