Cholicamideβ

SKU:BHB21902120
Overview
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Cholicamideβ (CAS 3036578-71-6) is a bioactive small molecule. Relevant to Apoptosis research. Molecular formula C55H94N2O6, molecular weight 879.34 g/mol.
CAS Number 3036578-71-6
Molecular Weight 879.34 g/mol
Storage See Certificate of Analysis
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Catalog no. Size
HY-156087-1MG 1 mg
HY-156087-5MG 5 mg
Available Options

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  • Options: Size: 1 mg, 5 mg
  • Lead time: confirmed on inquiry for every option.
  • Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
  • Shipping: Room temperature in continental US; may vary elsewhere.
  • Upon receipt: store as stated on the Certificate of Analysis; contact us if you need the condition before ordering.
Field Specification
CAS no. 3036578-71-6
Applications
  • Functional Assay (In Vitro)
Molecular weight 879.34
Molecular formula C55H94N2O6
SMILES [H][C@]12C[C@@H]([C@@]3([C@H](CC[C@]3([C@]1([H])CC[C@@]4(C[C@@H](CC[C@]24C)O)[H])[H])[C@@H](CCC(NCCCCCCCNC(CC[C@H]([C@@H]5[C@@]6(C)[C@@H](O)C[C@@]7([H])[C@@](CC[C@@]8(C[C@@H](CC[C@@]87C)O)[H])([C@@]6(CC5)[H])[H])C)=O)=O)C)C)O
Storage Refer to Certificate of Analysis (CoA) for storage conditions
Shipping Room temperature in continental US; may vary elsewhere.
Catalog no. (Mfr.) HY-156087
Main SKU BHB21902120
Bioactive Small Molecules

Compound Overview

Cholicamideβ, produced as a GMP-grade material is a self-assembling small-molecule cancer vaccine adjuvant. It can form virus-like particles with low cytotoxicity and, upon binding peptide antigens, enhances antigen presentation by dendritic cells and induces antigen-specific T cells; it can also induce apoptosis and necrosis[1]. It has a molecular formula of C55H94N2O6 and a molecular weight of 879.34 g/mol.

Physical & Chemical Properties

CAS Number 3036578-71-6
Molecular Formula C55H94N2O6
Molecular Weight 879.34 g/mol
SMILES [H][C@]12C[C@@H]([C@@]3([C@H](CC[C@]3([C@]1([H])CC[C@@]4(C[C@@H](CC[C@]24C)O)[H])[H])[C@@H](CCC(NCCCCCCCNC(CC[C@H]([C@@H]5[C@@]6(C)[C@@H](O)C[C@@]7([H])[C@@](CC[C@@]8(C[C@@H](CC[C@@]87C)O)[H])([C@@]6(CC5)[H])[H])C)=O)=O)C)C)O
Signaling Pathway Apoptosis
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping Room temperature in continental US; may vary elsewhere.

Literature Cited

Sources cited in this description and in the In Vitro & In Vivo Data tab. Peer-reviewed publications that used this product are listed under References.

[1]. Zhuo SH, et al. Identification of a Self-Assembling Small-Molecule Cancer Vaccine Adjuvant with an Improved Toxicity Profile. J Med Chem. 2023 Sep 7...

Safety

For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.

In Vitro

Cholicamideβ (4-16 μM; 22 h) induces both apoptosis and necrosis in RAW264.7 cells[1].

In Vivo

In C57BL/6 mice immunized with split influenza vaccine, Cholicamideβ at 100 μg/mouse (tested after 16 h and 21 d) increases HA-specific IgG antibody titers and shows low toxicity[1].

Data provided by the manufacturer. Numbered citations refer to the Literature Cited list in the product description.

Q.Why is there no price listed?
A.Every size of this product is quoted on inquiry. Send us the size you need and we will come back with price and lead time.
Q.Can this be used in humans or for diagnostics?
A.No. This product is supplied For Research Use Only. It is not for diagnostic or therapeutic procedures and not for human or veterinary use.

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