CHPG sodium salt

SKU:BHB20401525
Overview
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CHPG sodium salt (CAS 1303993-73-8) is a nf-κb pathway inhibitor supplied as a solid powder by TargetMol. For biochemical profiling and cell-based assay applications.
Activity NF-κB Pathway Inhibitor
CAS No. 1303993-73-8
Molecular Weight 223.59 g/mol
Form Solid
Shipping Room Temperature
Options selector
Catalog no. Size
T10808-1MG 1 mg
T10808-1MLX10MM 1 mL x 10 mM (in DMSO)
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 1 mg, 1 mL x 10 mM (in DMSO)
  • Lead time: In Stock at Manufacturer — options listed in "Availability Content"; other statuses may take longer.
  • Storage: −20 °C
  • Shipping: Room temperature (RT) shipment.
  • Upon receipt: Store at −20 °C as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Mfr No T10808
Activity
  • NF-κB Pathway Inhibitor
Cas No. 1303993-73-8
Molecular Weight 223.59
Product Type
  • Small Molecule Inhibitor
Signaling Pathway Neuroscience///NF-kappab
SMILES C1=CC(=C(C=C1O)C(C(=O)(O-))N)Cl.(Na+)
Target NF-kappaB///GluR

Compound Overview

CHPG sodium salt (CAS 1303993-73-8) is a research-grade small molecule supplied by TargetMol.

Physical Properties

CAS Number 1303993-73-8
Molecular Formula C8H7ClNNaO3
Molecular Weight 223.59 g/mol
SMILES C1=CC(=C(C=C1O)C(C(=O)(O-))N)Cl.(Na+)
Form Solid
Shipping Room Temperature (RT)

Biological Activity

CHPG sodium salt is a selective agonist of mGluR5 and activates the ERK and Akt signaling pathways. CHPG sodium salt can be used in studies about traumatic brain injury.

Target(s): NF-kappaB, GluR

Signaling pathway(s): Neuroscience, NF-kappab

Safety & Regulatory

For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.

What's the meaning of "< 1 mg/mL refers to the slightly soluble or insoluble"?

When solubility is listed as < 1 mg/mL, the compound dissolves to less than 1 mg per milliliter in water at 25 °C, pH 7.4. Such compounds require an organic co-solvent such as DMSO to prepare a concentrated stock, which is then diluted into aqueous assay buffer. For cell-based assays, keep the final DMSO concentration below 0.1% (v/v) to avoid solvent-induced cytotoxicity.

Why can't I see anything in the vial when I receive small-sized products?

Due to the small pack, the powder may be highly dispersed during shipping due to static electricity and may adhere to the vial. Please centrifuge and add an appropriate solvent to fully dissolve the product and prepare the stock solution.

Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.

  • Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
  • Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
  • Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
  • QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
  • Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).

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Send the CAS or structure and your specs. We can help source it, suggest close equivalents, or discuss custom synthesis with the right QC documentation (RUO).

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Experience the power of Celltrypse™, c-LEcta's innovative enzyme solution for gentle and efficient cell dissociation. Request your free sample and discover a superior alternative for your cell culture workflows.

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