Corydamine

SKU:BHB21902806
Overview
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Corydamine (CAS 49870-84-0) is a natural product. Reported to act on Topoisomerase I, Topoisomerase II. Relevant to Cell Cycle/DNA Damage research. Molecular formula C20H18N2O4, molecular weight 350.37 g/mol.
CAS Number 49870-84-0
Molecular Weight 350.37 g/mol
Target Topoisomerase I, Topoisomerase II
Storage See Certificate of Analysis
Options selector
Catalog no. Size
HY-N10367-50MG 50 mg
HY-N10367-100MG 100 mg
HY-N10367-250MG 250 mg
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 50 mg, 100 mg, 250 mg
  • Lead time: confirmed on inquiry for every option.
  • Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
  • Shipping: Room temperature in continental US; may vary elsewhere.
  • Upon receipt: store as stated on the Certificate of Analysis; contact us if you need the condition before ordering.
Field Specification
Target Topoisomerase I, Topoisomerase II
CAS no. 49870-84-0
Applications
  • Functional Assay (In Vitro)
Source Plant — Papaveraceae Corydalis bulleyana Diels
Molecular weight 350.37
Molecular formula C20H18N2O4
SMILES CNCCC1=C(C2=CC3=C(C=N2)C(OCO4)=C4C=C3)C=C(OCO5)C5=C1
Storage Refer to Certificate of Analysis (CoA) for storage conditions
Shipping Room temperature in continental US; may vary elsewhere.
Catalog no. (Mfr.) HY-N10367
Main SKU BHB21902806
Natural Products

Compound Overview

Corydamine, a 3-arylisoquinoline alkaloid, is a potent inhibitor of DNA topoisomerase I/II. It has anti-cancer activity[1]. It has the formula C20H18N2O4 and a molecular weight of 350.37 g/mol.

Physical & Chemical Properties

CAS Number 49870-84-0
Molecular Formula C20H18N2O4
Molecular Weight 350.37 g/mol
Structure Classification Alkaloids Isoquinoline Alkaloids
SMILES CNCCC1=C(C2=CC3=C(C=N2)C(OCO4)=C4C=C3)C=C(OCO5)C5=C1
Target Topoisomerase I, Topoisomerase II
Signaling Pathway Cell Cycle/DNA Damage
Initial Source Plant — Papaveraceae Corydalis bulleyana Diels
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping Room temperature in continental US; may vary elsewhere.

Literature Cited

Sources cited in this description. Peer-reviewed publications that used this product are listed under References.

[1]. Xuemei Deng, et al. Design, synthesis and anti-hepatocellular carcinoma activity of 3-arylisoquinoline alkaloids. Eur J Med Chem. 2022 Jan 15;228:113985.

Safety

For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.

Q.Why is there no price listed?
A.Every size of this product is quoted on inquiry. Send us the size you need and we will come back with price and lead time.
Q.Can this be used in humans or for diagnostics?
A.No. This product is supplied For Research Use Only. It is not for diagnostic or therapeutic procedures and not for human or veterinary use.

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