| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | Cytochrome c oxidase subunit 3 ;Cytochrome c oxidase polypeptide III |
| Clonality | |
| Concentration | |
| Formulation | |
| Gene ID | |
| Host | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 1-80 |
| Isotype | |
| Product Type | |
| Reactivity | |
| Storage | |
| Target |
Product Overview
Primary AntibodyThis antibody targets MT-CO3 and detects endogenous levels of MT-CO3 protein.
Validated Applications
| Application | Dilution Guidance |
|---|---|
| Western Blot (WB) | Refer to datasheet for recommended working dilution |
| ELISA | Refer to datasheet for recommended working dilution |
Antibody Specifications
| Target | MT-CO3 |
|---|---|
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Reactivity | Human, Rat, Mouse |
| Purification | Affinity Purification |
| Concentration | 1 mg/ml |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 1-80 |
| Formulation | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Storage | -20°C for 1 year |
| Gene ID | Human: 4514 |
| UniProt | P00414 (Human: P00414; Mouse: P00416; Rat: P05505) |
Scientific Background
Cytochrome c oxidase subunit III (COX3) is an enzyme that in humans is encoded by the MT-CO3 gene. It is one of main transmembrane subunits of cytochrome c oxidase. Cytochrome c oxidase subunit III is also one of the three mitochondrial DNA (mtDNA) encoded subunits (MT-CO1, MT-CO2, MT-CO3) of respiratory complex IV. Variants of MT-CO3 have been associated with isolated myopathy, severe encephalomyopathy, Leber hereditary optic neuropathy, mitochondrial complex IV deficiency, and recurrent myoglobinuria .
Alternative Names
Cytochrome c oxidase subunit 3 ;Cytochrome c oxidase polypeptide III
Safety & Handling
| Target | MT-CO3 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Reactivity | Human, Rat, Mouse |
| Purification | Affinity Purification |
| Concentration | 1 mg/ml |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 1-80 |
| Formulation | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Storage | -20°C for 1 year |
| Gene ID | Human: 4514 |
| UniProt | P00414 (Human: P00414; Mouse: P00416; Rat: P05505) |
Optimized working dilutions depend on sample type and detection system. Titration is recommended.
| Application | Dilution Note |
|---|---|
| Western Blot (WB) | Refer to datasheet for recommended working dilution |
| ELISA | Refer to datasheet for recommended working dilution |
Cytochrome c oxidase subunit III (COX3) is an enzyme that in humans is encoded by the MT-CO3 gene. It is one of main transmembrane subunits of cytochrome c oxidase. Cytochrome c oxidase subunit III is also one of the three mitochondrial DNA (mtDNA) encoded subunits (MT-CO1, MT-CO2, MT-CO3) of respiratory complex IV. Variants of MT-CO3 have been associated with isolated myopathy, severe encephalomyopathy, Leber hereditary optic neuropathy, mitochondrial complex IV deficiency, and recurrent myoglobinuria .
Alternative Names
Cytochrome c oxidase subunit 3 ;Cytochrome c oxidase polypeptide III
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
