| Field | Specification |
|---|---|
| Mfr No | |
| Clonality | |
| Host | |
| Immunogen | A synthesized peptide derived from human CSDE1 was used as the immunogen for the CSDE1 antibody. |
| Isotype | |
| Product Type | |
| Purity | |
| Reactivity | |
| Storage | |
| Target | |
| UniProt # |
Overview
CSDE1 Antibody / Cold shock domain containing E1 is a anti-CSDE1 Rabbit antibody Recombinant Rabbit Monoclonal clone 30C82 supplied in Liquid format. Recommended for workflows such as Western blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP) with listed reactivity in Human, Mouse, Rat.
Key elements and design rationale
- Target: CSDE1
- Antibody details: Rabbit, Recombinant Rabbit Monoclonal, clone 30C82, isotype Rabbit IgG
- Format: Liquid
- Applications (as listed): WB, IHC, ICC, IF, IP
Biological background
CSDE1 antibody is widely applied in RNA biology, cancer research, and developmental studies. CSDE1 promotes internal ribosome entry site (IRES) mediated translation of select mRNAs, enabling protein synthesis during conditions when cap dependent translation is impaired. It also regulates RNA turnover and processing through interactions with RNA binding proteins and decay machinery. By detecting CSDE1, researchers can evaluate how RNA binding proteins integrate post transcriptional control of gene expression.
Western blot assays detect CSDE1 protein bands in cytoplasmic fractions, while immunohistochemistry maps its distribution across epithelial and neuronal tissues. Immunofluorescence highlights punctate localization in ribonucleoprotein granules, consistent with functions in RNA storage and processing. These methods allow detailed characterization of CSDE1 expression and function.
CSDE1 plays important roles in tumorigenesis. In melanoma and other cancers, CSDE1 promotes oncogene expression and suppresses tumor suppressor translation. Elevated CSDE1 levels correlate with tumor progression, invasion, and metastasis. By applying CSDE1 antibody, scientists can investigate how post transcriptional regulation contributes to cancer biology and therapy resistance.
Beyond oncology, CSDE1 is implicated in embryonic development, neuronal differentiation, and stress adaptation. It influences neuronal polarity and axon growth, as well as cellular responses to hypoxia and nutrient deprivation. These broad functions highlight the research value of CSDE1 antibody across multiple biological fields.
CSDE1 antibody from
Research relevance and current trends
- Connecting protein-level changes to phenotype using orthogonal readouts (genetic perturbation, transcriptomics, imaging).
- Considering isoforms and post-translational regulation when interpreting protein-level changes.
- Comparing results across species and model systems with matched controls.
Common research applications
- Western blotting: compare relative abundance and activation-state changes across conditions.
- Immunofluorescence: visualize subcellular distribution and cell-to-cell heterogeneity.
- Immunohistochemistry: map target signal in tissue context and compare regions/phenotypes.
Interpret changes in signal alongside appropriate controls and, when relevant, in parallel with total-protein or pathway readouts.
Notes for experimental interpretation
- Signal can reflect expression level, isoform composition, and post-translational state; interpret results in the context of your model system and stimuli.
- Species differences and sample matrices can influence epitope recognition; prioritize matched controls and orthogonal confirmation when feasible.
Antibody notes: Monoclonal antibodies provide a defined epitope recognition profile that can support consistent comparisons across experiments.
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
