| Field | Specification |
|---|---|
| Mfr No | |
| Enzyme Type | |
| Expression System | |
| Form | Liquid |
| Formulation | |
| Product Type | |
| Purity | |
| Source | HEK293 Cells |
| Species | |
| Storage | |
| Target |
Product Description
Cathepsin-D Human Recombinant
Overview
Cathepsin D is synthesized as a 54kDa precursor, which is proteolytically processed to an intermediate 48kDa single chain, which matures into more stable 34kDa and 14kDa two chain form. It is an estrogen-regulated lysosomal protease that has been suggested to facilitate cancer cell migration and invasion by digesting the basement membrane, extracellular matrix, and xonnective tissue. Because of its mitogenic and proteolytic activities, it has been implicated as a prognostic marker in many tumor types. Cathepsin D is expressed in epithelial cells as well as in macrophages.
Specifications
| Purity | Greater than 95% as determined by SDS-PAGE |
|---|---|
| Formulation | CTSD at 1mg/ml in 50mM MES, pH5.5, 100mM NaCl and 20% Glycerol. |
| Storage | Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months.Please prevent freeze-thaw cycles. |
| Expression System | HEK293 Cells |
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