Cyclo(Gly-Tyr)

SKU:BHB21900784
Research Validated
Overview
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Cyclo(Gly-Tyr) (CAS 5845-66-9) is a bioactive small molecule supplied as a solid. Relevant to Peptides research. Molecular formula C11H12N2O3, molecular weight 220.22 g/mol.
Purity 99.70%
CAS Number 5845-66-9
Molecular Weight 220.22 g/mol
Form Solid
Storage 4°C as supplied; in solvent -80°C
Options selector
Catalog no. Size
HY-131109-10MG 10 mg
HY-131109-25MG 25 mg
HY-131109-50MG 50 mg
HY-131109-100MG 100 mg
HY-131109-200MG 200 mg
HY-131109-500MG 500 mg
HY-131109-1MLX10MM 1 mL x 10 mM (in DMSO)
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 10 mg, 25 mg, 50 mg, 100 mg, 200 mg, 500 mg, 1 mL x 10 mM (in DMSO)
  • Lead time: varies by selected option.
  • Storage: 4°C, protect from light. In solvent: -80°C, 6 months; -20°C, 1 month (protect from light).
  • Shipping: Room temperature in continental US; may vary elsewhere.
  • Upon receipt: refrigerate at 4°C as soon as possible.
Field Specification
CAS no. 5845-66-9
Applications
  • Functional Assay (In Vitro)
Molecular weight 220.22
Molecular formula C11H12N2O3
Purity 99.70%
Form Solid
Storage 4°C, protect from light. In solvent: -80°C, 6 months; -20°C, 1 month (protect from light).
Shipping Room temperature in continental US; may vary elsewhere.
Catalog no. (Mfr.) HY-131109
Main SKU BHB21900784
Bioactive Small Molecules

Compound Overview

Cyclo(Gly-Tyr) is a cyclic dipeptide[1]. It is supplied as a white to off-white solid (C11H12N2O3, MW 220.22) at 99.70% purity.

Physical & Chemical Properties

CAS Number 5845-66-9
Molecular Formula C11H12N2O3
Molecular Weight 220.22 g/mol
Purity 99.70%
Appearance Solid
Color White to off-white
Sequence Cyclo(Gly-Tyr)
Sequence (one-letter) Cyclo(GY)
Signaling Pathway Peptides
Solubility In Vitro: DMSO: 31.25 mg/mL (141.90 mM; Requires sonication; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Storage 4°C, protect from light. In solvent: -80°C, 6 months; -20°C, 1 month (protect from light).
Shipping Room temperature in continental US; may vary elsewhere.

Literature Cited

Sources cited in this description. Peer-reviewed publications that used this product are listed under References.

[1]. Takashi Mizuma, et al. Uptake of Cyclic Dipeptide by PEPT1 in Caco-2 Cells: Phenolic Hydroxyl Group of Substrate Enhances Affinity for PEPT1. J Pharm Pharmacol. 2002 Sep;54(9):1293-6.

Safety

For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with the Safety Data Sheet and your institution's chemical hygiene plan.

In Vitro

SolventSolubilityNotes
DMSO31.25 mg/mL (141.90 mM)requires sonication; use freshly opened DMSO (absorbed moisture lowers solubility)

Aliquot the stock solution and store it at -80°C (up to 6 months) or -20°C (up to 1 month); protect from light; avoid repeated freeze-thaw cycles.

Data provided by the manufacturer.

Q.Why is there no price on some sizes?
A.Availability and lead time for those sizes are confirmed on inquiry. Send us the size you need and we will come back with price and lead time.
Q.Can this be used in humans or for diagnostics?
A.No. This product is supplied For Research Use Only. It is not for diagnostic or therapeutic procedures and not for human or veterinary use.

Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.

  • Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
  • Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
  • Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
  • QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
  • Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).

Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close equivalents, or discuss custom synthesis with the right QC documentation (RUO).

CDIS V1.0: A program for non-targeted rapid identification of cyclic dipeptides. J Chromatogr A 2025 Oct 25:1761:466402. PMID: 41014906

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