| Field | Specification |
|---|---|
| Alternative names | 4-{(2R)-2-[(1S,3S,5S)-3,5-Dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}-2,6-piperidinedione |
| CAS no. | |
| Applications | |
| Source | Synthetic |
| Molecular weight | |
| Molecular formula | C15H23NO4 |
| Purity | |
| Bioactivity | Inhibitor |
| Activity | |
| Solubility | Soluble to 50 mM in Ethanol and 25 mM in water |
| SMILES | |
| InChIKey | |
| Form | White solid |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Cycloheximide is a selective inhibitor of eukaryotic protein synthesis that blocks tRNA binding and release from ribosomes. It is widely used in neuroscience to study protein turnover, synaptic plasticity, and apoptosis. Cycloheximide-induced inhibition of translation provides insights into the role of de novo protein synthesis in memory formation and neurodegeneration.
Classification: Very toxic. May be fatal if inhaled, swallowed or absorbed through skin.
Safety Phrases:
- S22 - Do not breathe dust
- S24/25 - Avoid contact with skin and eyes
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
- S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible)
Risk Phrases:
- R26/27/28 - Very Toxic by inhalation, in contact with skin and if swallowed
- R62 - Possible risk of impaired fertility
- R68- Possible risk of irreversible effects
Hazard Phrases:
H300-H341-H360D-H411
Precautionary Phrases:
P201-P264-P273-P281-P301 + P310-P308 + P313
Cycloheximide (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-247)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
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