| Field | Specification |
|---|---|
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C25H30F5NO7 |
| Activity | |
| SMILES | |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
Cyclooctyne-O-amido-PEG3-PFP ester functions as a non-cleavable, 3-unit PEG linker in the synthesis of antibody-drug conjugates (ADCs)[1]. As a click chemistry reagent, it carries an alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAC) with molecules bearing azide groups. It has the molecular formula C25H30F5NO7 and a molecular weight of 551.50 g/mol.
Physical & Chemical Properties
| CAS Number | 2101206-33-9 |
|---|---|
| Molecular Formula | C25H30F5NO7 |
| Molecular Weight | 551.50 g/mol |
| SMILES | O=C(OC1=C(F)C(F)=C(F)C(F)=C1F)CCOCCOCCOCCNC(COC2C#CCCCCC2)=O |
| Signaling Pathway | Antibody-Drug Conjugate/ADC Related |
| Bioactivity Class | Non-cleavable Linker |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.
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