| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Cas No. | |
| Concentration | |
| Form | Lyophilized powder. |
| Product Type | |
| Purity | |
| Reconstitution | |
| Shipping | |
| Solubility | Water, DMSO, ethanol, methanol, acetone. Centrifuge all product preparations before use (10000 x g 5 min). |
| Source | Natural |
| Storage |
Product details
- Chemical name: 21,23-Dioxa[13]cytochalasa-13,19-diene-1,17,22- trione,6,7-epoxy-18-hydroxy-16,18-dimethyl-10-phenyl-,(7S,13E,16S,18R,19E)-.
- CAS number: 36011-19-5
- Molecular formula: C28H33NO7.
- Purity: >99%
- Concentration: 0.1-10 µM.
- Form: Lyophilized powder.
- Solubility: Water, DMSO, ethanol, methanol, acetone. Centrifuge all product preparations before use (10000 x g 5 min).
- Reconstitution: Water, DMSO, ethanol, methanol, acetone. Centrifuge all product preparations before use (10000 x g 5 min).
- Shipping: Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
- Source: Natural
- Activity: Cytochalasin E is a fungal toxin which inhibits actin polymerization and blocks the formation of microtubules by inhibiting cell division and cell migration1-4.
Scientific background
Cytochalasins are a group of fungal toxin metabolites which bind to actin and alter its polymerization. Cytochalasins bind to the barbed end of the actin filament and prevent both the association and dissociation of actin subunits by inhibiting cell microtubule formation, cell division and cell migration.1-4Cytochalasin E induced a rapid and sustained elevation of intracellular free Ca2+ in B lymphocytes by increasing the extracellular Ca2+ influx.5,6
Lead time: 1-2 Business Days
Country of origin: Israel/IL
Applications key
Application key: FC- Flow cytometry, IFC- Indirect flow cytometry, IHC- Immunohistochemistry,LCI- Live cell imaging, Calcium imaging assay,Cell survival assay, Electrophysiology, Neurite outgrowth assay.
Bioassay tested: Yes
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- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
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