| Field | Specification |
|---|---|
| Target | |
| Alternative names | KRT7; SCL; Keratin; type II cytoskeletal 7; Cytokeratin-7; CK-7; Keratin-7; K7; Sarcolectin; Type-II keratin Kb7 |
| Gene ID | |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | Purified recombinant human Cytokeratin 7 (C-terminus) protein fragments expressed in E.coli. |
| Conjugate | |
| Purification | |
| Concentration | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Scientific Background
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants| however, not all variants have been fully described.
Product Overview
This monoclonal antibody, raised in Mouse, recognizes KRT7. It is validated for Western Blot, Immunofluorescence.
Validated Applications
| Applications | Western Blot, Immunofluorescence |
|---|
Optimal dilutions should be determined by the end user for each application and sample type.
Immunogen
Purified recombinant human Cytokeratin 7 (C-terminus) protein fragments expressed in E.coli.
Specifications
| Host | Mouse |
|---|---|
| Clonality | Monoclonal |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat, Dog |
| Immunogen | Purified recombinant human Cytokeratin 7 (C-terminus) protein fragments expressed in E.coli. |
| Purification | Affinity purification |
| Concentration | 1 mg/ml |
| Formulation | Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol. |
| UniProt Accession | Human: P08729; Mouse: Q9DCV7; Rat: Q6IG12 |
| Gene ID | Human: 3855; Mouse: 110310; Rat: 300242 |
| Storage | -20°C for 1 year |
| Lead Time | Within one week |
Reactivity Notes
Validated reactivity: Human, Mouse, Rat, Dog. For other species, epitope conservation may allow cross-reactivity; confirm with appropriate controls.
Safety & Handling
This product is for research use only (RUO) and is not intended for diagnostic or therapeutic use. The formulation contains sodium azide; handle with standard laboratory precautions.
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Explore related antibodies and reagents for KRT7 research from Bioassay Technology Laboratory, or contact us for alternative formats.
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