| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | N6,O2'-Dibutyryl adenosine 3',5'-cyclic monophosphate sodium salt; Bucladesine Na |
| Cas No. | |
| Form | White to off-white powder |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | May be dissolved in DMSO (50 mg/ml); water (50 mg/ml) |
| Source | Synthetic |
| Storage |
Dibutyryl-cAMP is a cell-permeable analog of cyclic AMP that mimics endogenous cAMP signaling. It activates protein kinase A (PKA) and promotes morphological differentiation of astrocytes and dopaminergic neurons. In stem cell research, it is used to induce neuronal differentiation and maturation. Dibutyryl-cAMP is a valuable tool in neuroscience for studying cAMP-mediated signaling pathways and their roles in neurodevelopment and neurodegenerative disease models.
Details:
No hazard pictogram, no signal word, no hazard statement(s), no precautionary statement(s) required
Dibutyryl-cAMP (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-632)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
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2. ML Carranza et al. J. Physiol. 1998 15:511
3. YJ Hei et al. Mol. Pharmacol. 1991 39:233
4. M Imamura et al. Proc. Natl. Acad. Sci. USA 1998 95:6139
5. N Xia et al. Sci. Rep. 2016 6:20270
