DMNPE-4 AM-caged-calcium

SKU:BHB21900978
Overview
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DMNPE-4 AM-caged-calcium (CAS 2253744-58-8) is a bioactive small molecule. Relevant to Membrane Transporter/Ion Channel and Neuronal Signaling research. Molecular formula C34H47N3O22, molecular weight 849.74 g/mol.
CAS Number 2253744-58-8
Molecular Weight 849.74 g/mol
Storage See Certificate of Analysis
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Catalog no. Size
HY-136283-5MG 5 mg
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 5 mg
  • Lead time: made to order; typically ships within 2–3 weeks.
  • Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
  • Shipping: Room temperature in continental US; may vary elsewhere.
  • Upon receipt: store as stated on the Certificate of Analysis; contact us if you need the condition before ordering.
Field Specification
CAS no. 2253744-58-8
Applications
  • Functional Assay (In Vitro)
Molecular weight 849.74
Molecular formula C34H47N3O22
SMILES O=C(CN(CCOCCOC(C1=C([N+]([O-])=O)C=C(OC)C(OC)=C1)CN(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O)OCOC(C)=O
Storage Refer to Certificate of Analysis (CoA) for storage conditions
Shipping Room temperature in continental US; may vary elsewhere.
Catalog no. (Mfr.) HY-136283
Main SKU BHB21900978
Bioactive Small Molecules

Compound Overview

DMNPE-4 AM-caged-calcium, a photolabile analogue of EGTA, is an extremely effective Ca2+-selective cage, with a Kd for Ca2+ of 48 nM at pH 7.2 and 19 nM at pH 7.4. After photolysis, its affinity for Ca2+ decreases to a Kd of approximately 2 nM[1][2]. It has the molecular formula C34H47N3O22 and a molecular weight of 849.74 g/mol.

Physical & Chemical Properties

CAS Number 2253744-58-8
Molecular Formula C34H47N3O22
Molecular Weight 849.74 g/mol
SMILES O=C(CN(CCOCCOC(C1=C([N+]([O-])=O)C=C(OC)C(OC)=C1)CN(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O)OCOC(C)=O
Signaling Pathway Membrane Transporter/Ion Channel; Neuronal Signaling
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping Room temperature in continental US; may vary elsewhere.

Literature Cited

Sources cited in this description. Peer-reviewed publications that used this product are listed under References.

[1]. Ellis-Davies GCR, et al. Tuning caged calcium: photolabile analogues of EGTA with improved optical and chelation properties. Cell Calcium. 2006 Jan;39(1):75-83.

[2]. DelPrincipe F, et al. Two-photon and UV-laser flash photolysis of the Ca2+ cage, dimethoxynitrophenyl-EGTA-4. Cell Calcium. 1999 Jan;25(1):85-91.

Safety

For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.

Q.How long does this take to ship?
A.This item is produced on request and typically ships within 2–3 weeks.
Q.Can this be used in humans or for diagnostics?
A.No. This product is supplied For Research Use Only. It is not for diagnostic or therapeutic procedures and not for human or veterinary use.

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