| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | 5,7-Dimethoxy-3-(4-pyridinyl)quinoline dihydrochloride |
| Cas No. | |
| Form | White to beige solid |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | Soluble to 100 mM in water |
| Source | Synthetic |
| Storage |
DMPQ Dihydrochloride is a potent and selective inhibitor of platelet-derived growth factor receptor beta (PDGFRβ) tyrosine kinase. In neuroscience, PDGFRβ signaling is involved in neurovascular function, blood-brain barrier maintenance, and glial cell regulation. DMPQ is used to study the role of PDGFRβ in neuroinflammation, pericyte function, and neurovascular remodeling in diseases such as Alzheimer’s and stroke. Its high selectivity over other kinases makes it a valuable tool for dissecting PDGFRβ-mediated pathways in the central nervous system.
Classification: Acute toxicity, Oral (Category 4)
Safety Phrases:
- S22 - Do not breathe dust.
- S24/25 - Avoid contact with skin and eyes.
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
Hazard statements:
H302 Harmful if swallowed.
DMPQ Dihydrochloride (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-441)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
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