| Field | Specification |
|---|---|
| Mfr No | |
| Clonality | |
| Host | |
| Immunogen | E.coli-derived mouse DNMT2/TRDMT1 recombinant protein (Position: M16-E391) was used as the immunogen for the Dnmt2 antibody. |
| Isotype | |
| Product Type | |
| Purity | |
| Reactivity | |
| Storage | |
| Target | |
| UniProt # |
Overview
Dnmt2 Antibody / DNA methyltransferase 2 / TRDMT1 is an antibody targeting Dnmt2. Host: Rabbit. Polyclonal. Format: Lyophilized. Applications: WB, FACS, ELISA.
Key elements and design rationale
- Target: Dnmt2.
- Immunogen: E.coli-derived mouse DNMT2/TRDMT1 recombinant protein (Position: M16-E391) was used as the immunogen for the Dnmt2 anti….
- Species reactivity: Mouse, Rat.
- Conjugate: Unconjugated (no label listed).
Biological background (from provided description)
DNMT2 antibody detects DNA methyltransferase homolog 2, encoded by the TRDMT1 gene on chromosome 10p15.1. DNMT2 antibody is applied in research on epigenetics, RNA modification, and gene regulation. Although named DNA methyltransferase 2, DNMT2 primarily functions as an RNA methyltransferase that catalyzes cytosine-5 methylation at tRNA-Asp and other tRNAs, influencing translation fidelity and stability.
Common research applications
- WB: relative abundance and band pattern assessment using appropriate controls.
Notes for experimental interpretation
- Account for isoforms, paralogs, and post-translational modifications when interpreting signal.
- Support specificity with biological controls (e.g., KO/KD where available) and technical controls (e.g., secondary-only/isotype).
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
