| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | (2α,5β,7β,10β,13α)-4-Acetoxy-1,7,10-trihydroxy-13-{[(2R,3S)-2-hydroxy-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-3-phenylpropanoyl]oxy}-9-oxo-5,20-epoxytax-11-en-2-yl benzoate |
| Cas No. | |
| Form | White solid |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | Soluble to 100 mM in DMSO, and to 100 mM in ethanol |
| Source | Synthetic |
| Storage |
Docetaxel is a semi-synthetic analogue of paclitaxel that binds and stabilizes microtubules, resulting in cell cycle arrest and apoptosis. In neurodegenerative disease research, docetaxel is used to investigate microtubule-targeting strategies and their effects on neuronal integrity. Its ability to interfere with mitotic processes and induce apoptosis has made it a valuable tool in understanding neurotoxicity and axonal degeneration.
Classification: Caution: Substance not yet fully tested.
Safety Phrases:
- S22 - Do not breathe dust
- S24/25 - Avoid contact with skin and eyes
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
Docetaxel (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-240)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
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equivalents, or discuss custom synthesis with the right QC documentation (RUO).
2. Woodward E.J. and Twelves C. (2010) Curr. Clin Pharmacol. 5(3): 226-231.
