Dolastatinol

SKU:BHB21901115
Overview
Click light‑blue chips for details
Dolastatinol (CAS 2759918-83-5) is a tubulin polymerization inhibitor. Relevant to Cell Cycle/DNA Damage and Cytoskeleton research. Molecular formula C43H70N6O7S, molecular weight 815.12 g/mol.
CAS Number 2759918-83-5
Molecular Weight 815.12 g/mol
Storage See Certificate of Analysis
Options selector
Catalog no. Size
HY-139625-50MG 50 mg
HY-139625-100MG 100 mg
HY-139625-250MG 250 mg
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 50 mg, 100 mg, 250 mg
  • Lead time: confirmed on inquiry for every option.
  • Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
  • Shipping: Room temperature in continental US; may vary elsewhere.
  • Upon receipt: store as stated on the Certificate of Analysis; contact us if you need the condition before ordering.
Field Specification
CAS no. 2759918-83-5
Applications
  • Functional Assay (In Vitro)
Molecular weight 815.12
Molecular formula C43H70N6O7S
SMILES OCC1=CSC([C@H](CC2=CC=CC=C2)NC([C@@H](C)[C@@H]([C@]3([H])N(CCC3)C(C[C@H](OC)[C@H]([C@H](C)CC)N(C)C([C@@H](C(C)C)NC([C@H](N(C)C)C(C)C)=O)=O)=O)OC)=O)=N1
Storage Refer to Certificate of Analysis (CoA) for storage conditions
Shipping Room temperature in continental US; may vary elsewhere.
Catalog no. (Mfr.) HY-139625
Main SKU BHB21901115
Inhibitors

Compound Overview

Dolastatinol is a synthetic analog of dolastatin 10 and a low-nanomolar inhibitor of tubulin polymerization. The compound has the molecular formula C43H70N6O7S and a molecular weight of 815.12 g/mol.

Physical & Chemical Properties

CAS Number 2759918-83-5
Molecular Formula C43H70N6O7S
Molecular Weight 815.12 g/mol
SMILES OCC1=CSC([C@H](CC2=CC=CC=C2)NC([C@@H](C)[C@@H]([C@]3([H])N(CCC3)C(C[C@H](OC)[C@H]([C@H](C)CC)N(C)C([C@@H](C(C)C)NC([C@H](N(C)C)C(C)C)=O)=O)=O)OC)=O)=N1
Signaling Pathway Cell Cycle/DNA Damage; Cytoskeleton
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping Room temperature in continental US; may vary elsewhere.

Literature Cited

Sources cited in this description. Peer-reviewed publications that used this product are listed under References.

[1]. Gutman H, et al. Discovery of Dolastatinol: A Synthetic Analog of Dolastatin 10 and Low Nanomolar Inhibitor of Tubulin Polymerization. ACS Med Chem Lett. 2021 Sep 7;12(10):1596-1604.

Safety

For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.

Q.Why is there no price listed?
A.Every size of this product is quoted on inquiry. Send us the size you need and we will come back with price and lead time.
Q.Can this be used in humans or for diagnostics?
A.No. This product is supplied For Research Use Only. It is not for diagnostic or therapeutic procedures and not for human or veterinary use.

Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.

  • Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
  • Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
  • Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
  • QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
  • Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).

Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close equivalents, or discuss custom synthesis with the right QC documentation (RUO).

Get a Quote

Please use this form for bulk quantity requests or customized products.

Contact Information

Product Information

Try Celltrypse Free – Request Your Sample Today

Experience the power of Celltrypse™, c-LEcta's innovative enzyme solution for gentle and efficient cell dissociation. Request your free sample and discover a superior alternative for your cell culture workflows.

Try Celltrypse Free – Request Your Sample Today

Try Celltrypse Free – Request Your Sample Today

Experience the power of Celltrypse™, c-LEcta's innovative enzyme solution for gentle and efficient cell dissociation. Request your free sample and discover a superior alternative for your cell culture workflows.

Try Celltrypse Free – Request Your Sample Today