Duloxetine Hydrochloride

SKU:BHB11900327
Suppliers
StressMarq Biosciences Inc.
StressMarq Biosciences Inc.
Details Products
Overview
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Duloxetine Hydrochloride is a research-grade small-molecule inhibitor of 5-HT-noradrenaline reuptake supporting Neuroscience and Neurotransmitter Receptors research. Supplied as a white powder with >98% purity (CAS 136434-34-9, MW 333.9) dissolvable in DMSO; store at -20°C. For research use only.
Cas No. 136434-34-9
Molecular Formula C18H19NOS.HCl
Purity >98% (TLC); NMR (Conforms)
Application Notes 5-HT-noradrenaline reuptake inhibitor
Options selector
Catalog no. Size
SIH-549-10MG 10 mg
SIH-549-50MG 50 mg
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size (2) — 10 mg, 50 mg.
  • Lead time: options listed as “in stock at manufacturer” typically ship in 2-3 business days; other statuses may take longer.
  • Storage: -20ºC
  • Shipping: ships at ambient temperature.
  • Upon receipt: store at the recommended temperature as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Alternative names Duloxetine Hydrochloride, (+)-(S)-N-Methyl-3-(1-naphthyloxy)-3-(2-thienyl)propanamine hydrochloride, (S)-Duloxetine hydrochloride, (γS)-N-Methyl-γ-(1-naphthalenyloxy)-2-thiophenepropanamine hydrochloride, (+)-(S)-N-Methyl-γ-(1-naphthyloxy)-2-thiophenepropylamine hydrochloride, (+)-N-Methyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine hydrochloride, (3S)-N-methyl-3-naphthalen-1-yloxy-3-thiophen-2-ylpropan-1-amine;hydrochloride, Duloxetine HCl
CAS no. 136434-34-9
Applications
  • Functional Assay (In Vitro)
Source Synthetic
Molecular weight 333.9
Molecular formula C18H19NOS.HCl
Purity >98% (TLC); NMR (Conforms)
Bioactivity Inhibitor
Activity
  • Inhibitor
Solubility May be dissolved in DMSO (30 mg/ml); or water (3 mg/ml)
SMILES CNCCC(C1=CC=CS1)OC2=CC=CC3=CC=CC=C32.Cl
InChIKey BFFSMCNJSOPUAY-LMOVPXPDSA-N
Form White powder
Storage -20ºC
Shipping Shipped Ambient
Catalog no. (Mfr.) SIH-549
Main SKU BHB11900327

Duloxetine hydrochloride is a serotonin-norepinephrine reuptake inhibitor (SNRI) widely used in the treatment of depression and neuropathic pain. In neurodegenerative disease research, Duloxetine has been investigated for its ability to modulate neuroinflammation, enhance neuroplasticity, and protect against neuronal loss. Its dual-action mechanism on monoaminergic pathways supports its use in managing cognitive and emotional symptoms associated with neurodegenerative disorders.

WHMIS Classification: Not WHMIS controlled.

GHS Classification: Acute toxicity, Oral (Category 4)

Signal word:

Warning

Hazard statement(s):

  • H302 Harmful if swallowed.
  • Precautionary statement(s) none

Health hazard:

1

Flammability:

0

Physical hazards:

0

Potential Health Effects: Inhalation - May be harmful if inhaled. May cause respiratory tract irritation.

Skin - Harmful if absorbed through skin. May cause skin irritation.

Eyes - May cause eye irritation.

Ingestion - Harmful if swallowed.

Duloxetine Hydrochloride (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-549)

Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.

  • Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
  • Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
  • Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
  • QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
  • Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).

Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close equivalents, or discuss custom synthesis with the right QC documentation (RUO).

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