| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | Duloxetine Hydrochloride, (+)-(S)-N-Methyl-3-(1-naphthyloxy)-3-(2-thienyl)propanamine hydrochloride, (S)-Duloxetine hydrochloride, (γS)-N-Methyl-γ-(1-naphthalenyloxy)-2-thiophenepropanamine hydrochloride, (+)-(S)-N-Methyl-γ-(1-naphthyloxy)-2-thiophenepropylamine hydrochloride, (+)-N-Methyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine hydrochloride, (3S)-N-methyl-3-naphthalen-1-yloxy-3-thiophen-2-ylpropan-1-amine;hydrochloride, Duloxetine HCl |
| Cas No. | |
| Form | White powder |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | May be dissolved in DMSO (30 mg/ml); or water (3 mg/ml) |
| Source | Synthetic |
| Storage |
Duloxetine hydrochloride is a serotonin-norepinephrine reuptake inhibitor (SNRI) widely used in the treatment of depression and neuropathic pain. In neurodegenerative disease research, Duloxetine has been investigated for its ability to modulate neuroinflammation, enhance neuroplasticity, and protect against neuronal loss. Its dual-action mechanism on monoaminergic pathways supports its use in managing cognitive and emotional symptoms associated with neurodegenerative disorders.
WHMIS Classification: Not WHMIS controlled.
GHS Classification: Acute toxicity, Oral (Category 4)
Signal word:
Warning
Hazard statement(s):
- H302 Harmful if swallowed.
- Precautionary statement(s) none
Health hazard:
1
Flammability:
0
Physical hazards:
0
Potential Health Effects: Inhalation - May be harmful if inhaled. May cause respiratory tract irritation.
Skin - Harmful if absorbed through skin. May cause skin irritation.
Eyes - May cause eye irritation.
Ingestion - Harmful if swallowed.
Duloxetine Hydrochloride (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-549)
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- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
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- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
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