| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | Dynasore, Dynamin Inhibitor I, 3-Hydroxynaphthalene-2-carboxylic acid (3,4-dihydroxybenzylidene)hydrazide, 3-hydroxy-N'-[(E)-(3-hydroxy-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]naphthalene-2-carbohydrazide |
| Cas No. | |
| Form | Beige powder |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | May be dissolved in DMSO (30 mg/ml, warm); or ethanol (1 mg/ml). |
| Source | Synthetic |
| Storage |
Dynasore is a cell-permeable inhibitor of dynamin GTPases, which are essential for clathrin-mediated endocytosis. In neuroscience, Dynasore is used to study synaptic vesicle recycling, membrane trafficking, and neurodegenerative mechanisms involving endocytic dysfunction. Its ability to transiently block endocytosis makes it a valuable tool for dissecting cellular pathways implicated in Alzheimer’s and Parkinson’s disease models.
WHMIS Classification: Not WHMIS controlled.
GHS Classification: Eye irritation (Category 2B)
Acute aquatic toxicity (Category 1)
Hazard statement(s):
- H320 Causes eye irritation.
- H400 Very toxic to aquatic life.
Precautionary statement(s):
- P273 Avoid release to the environment.
- P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Potential Health Effects: Inhalation - May be harmful if inhaled. May cause respiratory tract irritation.
Skin - May be harmful if absorbed through skin. May cause skin irritation.
Eyes - May cause eye irritation.
Ingestion - May be harmful if swallowed.
Dynasore (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-550)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
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