| Field | Specification |
|---|---|
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C29H39N3O4 |
| SMILES | |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
E-2508 free base is an orally active, highly selective corticotropin-releasing factor type 1 receptor (CRF1) antagonist with anxiolytic effects (Ki 11 nM) that blocks CRF-induced cAMP accumulation via CRF1 receptor inhibition. It is promising for research into stress-related psychiatric disorders such as anxiety and depression[1]. It has the molecular formula C29H39N3O4 and a molecular weight of 493.64 g/mol.
Physical & Chemical Properties
| CAS Number | 685885-75-0 |
|---|---|
| Molecular Formula | C29H39N3O4 |
| Molecular Weight | 493.64 g/mol |
| SMILES | CCC1=NN2C(C3=C(C=C(C=C3OC)COC)OC)=CC=CC2=C1N(CC4CCOCC4)CC5CC5 |
| Signaling Pathway | GPCR/G Protein |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.
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