eIF4E-IN-5

SKU:BHB21902067
Overview
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eIF4E-IN-5 is an eIF4E inhibitor. Relevant to Cell Cycle/DNA Damage research. Molecular formula C30H39Cl2N6O8P, molecular weight 713.55 g/mol.
Molecular Weight 713.55 g/mol
Storage See Certificate of Analysis
Options selector
Catalog no. Size
HY-155676-50MG 50 mg
HY-155676-100MG 100 mg
HY-155676-250MG 250 mg
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 50 mg, 100 mg, 250 mg
  • Lead time: confirmed on inquiry for every option.
  • Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
  • Shipping: Room temperature in continental US; may vary elsewhere.
  • Upon receipt: store as stated on the Certificate of Analysis; contact us if you need the condition before ordering.
Field Specification
Applications
  • Functional Assay (In Vitro)
Molecular weight 713.55
Molecular formula C30H39Cl2N6O8P
SMILES NC1=NC2=C(C(N1)=O)[N+](CC3=CC4=C(N3)C=CC(Cl)=C4)=CN2C/C=C\CP(OCOC(C(C)(C)C)=O)(OCOC(C(C)(C)C)=O)=O.[Cl-]
Storage Refer to Certificate of Analysis (CoA) for storage conditions
Shipping Room temperature in continental US; may vary elsewhere.
Catalog no. (Mfr.) HY-155676
Main SKU BHB21902067
Inhibitors

Compound Overview

eIF4E-IN-5 is a cell-permeable inhibitor of eIF4E that can bind capped mRNA to inhibit cap-dependent translation[1]. It has the molecular formula C30H39Cl2N6O8P and a molecular weight of 713.55 g/mol.

Physical & Chemical Properties

Molecular Formula C30H39Cl2N6O8P
Molecular Weight 713.55 g/mol
SMILES NC1=NC2=C(C(N1)=O)[N+](CC3=CC4=C(N3)C=CC(Cl)=C4)=CN2C/C=C\CP(OCOC(C(C)(C)C)=O)(OCOC(C(C)(C)C)=O)=O.[Cl-]
Signaling Pathway Cell Cycle/DNA Damage
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping Room temperature in continental US; may vary elsewhere.

Literature Cited

Sources cited in this description. Peer-reviewed publications that used this product are listed under References.

[1]. Cárdenas EL, et al. Design of Cell-Permeable Inhibitors of Eukaryotic Translation Initiation Factor 4E (eIF4E) for Inhibiting Aberrant Cap-Dependent Translation in Cancer. J Med Chem. 2023 Aug 10;66(15):10734-10745.

Safety

For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.

Q.Why is there no price listed?
A.Every size of this product is quoted on inquiry. Send us the size you need and we will come back with price and lead time.
Q.Can this be used in humans or for diagnostics?
A.No. This product is supplied For Research Use Only. It is not for diagnostic or therapeutic procedures and not for human or veterinary use.

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  • Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
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Try Celltrypse Free – Request Your Sample Today

Experience the power of Celltrypse™, c-LEcta's innovative enzyme solution for gentle and efficient cell dissociation. Request your free sample and discover a superior alternative for your cell culture workflows.

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