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Scientific Background
CD16 is low affinity IgG Fc receptor III (FcR III) and CD32 is FcR II. CD16/CD32 are expressed on B cells, monocytes/macrophages, NK cells, granulocytes, mast cells, and dendritic cells. The Fc receptors bind antibody-antigen immune complexes and mediate adaptive immune responses.
Product Overview
This monoclonal antibody (clone 2.4G2), raised in Rat, recognizes CD16/32. It is validated for Flow Cytometry.
Validated Applications
| Applications | Flow Cytometry |
|---|
Optimal dilutions should be determined by the end user for each application and sample type.
Immunogen
See specifications table.
Specifications
| Host | Rat |
|---|---|
| Clonality | Monoclonal |
| Clone | 2.4G2 |
| Isotype | Rat IgG2b, κ |
| Conjugate | Elab Fluor® 647 |
| Species Reactivity | Mouse |
| Concentration | 5 μL/Test |
| Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| UniProt # | P08508;P08101 |
| Gene ID | 14130; 14131 |
| Control Catalog Number | E-AB-F09842M |
| Lead Time | 2-3 business days |
| Validity | 12 months |
| Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| Shipping | Ice packs |
| Target Synonyms | CD16a/b;CD32;CD32A/B;FCG2A;FCGR2A/BFCGR3;FCGR3A/B;Fc fragment of IgG low affinity IIIa/b receptor;Fc fragment of IgG low affinity IIIb receptor;Fc fragment of IgG low affinity IIa/b receptor;Fc gamma RIIa/bFc gamma receptor III A/B;FcGR |
Reactivity Notes
Validated reactivity: Mouse. For other species, epitope conservation may allow cross-reactivity; confirm with appropriate controls.
Safety & Handling
This product is for research use only (RUO) and is not intended for diagnostic or therapeutic use. The formulation contains sodium azide; handle with standard laboratory precautions.
Related Products
Explore related antibodies and reagents for CD16/32 research from Elabscience Biotechnology Co Ltd, or contact us for alternative formats.
Customization & Add-ons: Can't find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
