| Field | Specification |
|---|---|
| Alternative names | MM 45289; A 82846A |
| CAS no. | |
| Applications | |
| Source | Microbial — Amycolatopsis orientalis |
| Molecular weight | |
| Molecular formula | C73H89ClN10O26 |
| Purity | |
| SMILES | |
| Form | Solid |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
Eremomycin, also known as MM 45289 and A 82846A, is a potent glycopeptide antibiotic closely related to Vancomycin. It shows antibacterial activity against Staphylococcus spp. and Bacillus subtilis ATCC6633, with MIC values of 0.03-1.6 μg/mL[1]. It is supplied as a white to off-white solid (C73H89ClN10O26, MW 1557.99) at 95.87% purity.
Physical & Chemical Properties
| CAS Number | 110865-90-2 |
|---|---|
| Molecular Formula | C73H89ClN10O26 |
| Molecular Weight | 1557.99 g/mol |
| Purity | 95.87% |
| Appearance | Solid |
| Color | White to off-white |
| Structure Classification | Antibiotics |
| SMILES | C[C@@](N)([C@H]([C@@H](O1)C)O)C[C@@H]1O[C@@H]([C@]2([H])NC([C@](C3=CC=C(O)C(C4=C(O)C=C(O)C=C4[C@H](NC2=O)C(O)=O)=C3)([H])NC([C@]5([H])NC([C@@H](NC([C@@H]([C@@H](C6=CC=C(O7)C(Cl)=C6)O)NC([C@H](NC)CC(C)C)=O)=O)CC(N)=O)=O)=O)=O)C8=CC=C(C=C8)OC9=CC5=CC7=C9O[C@H]%10[C@@H]([C@H]([C@@H]([C@H](O%10)CO)O)O)O[C@H]%11C[C@](N)([C@H]([C@@H](O%11)C)O)C |
| Signaling Pathway | Anti-infection |
| Initial Source | Microbial — Amycolatopsis orientalis |
| Solubility | In Vitro: H2O: 100 mg/mL (64.19 mM; Requires sonication) |
| Storage | -20°C, protect from light. In solvent: -80°C, 6 months; -20°C, 1 month (protect from light). |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with the Safety Data Sheet and your institution's chemical hygiene plan.
In Vitro
| Solvent | Solubility | Notes |
|---|---|---|
| H2O | 100 mg/mL (64.19 mM) | requires sonication |
Aliquot the stock solution and store it at -80°C (up to 6 months) or -20°C (up to 1 month); protect from light; avoid repeated freeze-thaw cycles.
If water is used as the stock solvent, dilute to the working solution and sterilize it through a 0.22 μm filter before use.
Data provided by the manufacturer.
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