| Field | Specification |
|---|---|
| Alternative names | N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine hydrochloride |
| CAS no. | |
| Applications | |
| Source | Synthetic |
| Molecular weight | |
| Molecular formula | C22H24ClN3O4 |
| Purity | |
| Bioactivity | Inhibitor |
| Activity | |
| Solubility | Soluble in DMSO at 18 mg/ml with warming; very poorly soluble in ethanol; very poorly soluble in water; maximum solubility in plain water is estimated to be about 5-20 µM; buffers, serum, or other additives may increase or decrease the aqueous solubility |
| SMILES | |
| InChIKey | |
| Form | Solid powder |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Erlotinib Hydrochloride is a selective inhibitor of the epidermal growth factor receptor (EGFR/HER-1) tyrosine kinase. In neuroscience, EGFR signaling has been implicated in neuroinflammation, gliogenesis, and blood-brain barrier integrity. Erlotinib is used to explore the role of EGFR in neural cell proliferation, survival, and response to injury. Its ability to modulate receptor tyrosine kinase activity makes it a useful compound in studying neurovascular remodeling and neurodegenerative disease mechanisms involving aberrant EGFR signaling.
Classification: Not a hazardous substance or mixture.
Safety Phrases:
- S22 - Do not breathe dust.
- S24/25 - Avoid contact with skin and eyes.
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
Erlotinib Hydrochloride (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-444)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
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